Treating essential tremor with focused heat to both sides of the brain
Part of Brain & nervous system clinical trials.
This trial tests a one-time procedure that uses heat to stop the brain cells causing tremor. It might help people with severe shaking that hasn't improved with medication.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 20 and 70 years old.
- You have essential tremor (shaking) diagnosed by a movement disorder specialist.
- Standard tremor medicines like propranolol or primidone have not worked for you.
- You are able to have an MRI scan and are not pregnant or breastfeeding.
- You do not have a bleeding disorder or metal implants in your body.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a treatment that uses focused ultrasound waves to precisely target and calm the brain area causing your tremor — no surgery or incisions needed. If your tremor isn't well controlled by medication, this treatment might help reduce shaking and improve daily function.
This trial tests a new, non-invasive brain stimulation technique called transcranial temporal interference stimulation (tTIS) to see if it can reduce tremors in people with essential tremor. It is for people who are already candidates for a surgical treatment called MRI-guided focused ultrasound thalamotomy.
This trial tests a second focused ultrasound treatment for people with essential tremor who have already had one side treated. It checks if treating the other side helps control tremors better.
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This study tests whether a second focused ultrasound treatment on the other side of the brain can safely and effectively reduce tremor in people with essential tremor who already had one treatment. It's for those whose tremor is not well controlled by medication or previous treatments.
This study tests whether ultrasound waves applied to a part of the brain (the cerebellum) can safely affect brain activity. It involves healthy volunteers and people with essential tremor, a condition causing shaky hands, to see if this approach might help.
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