Clin2
NCT07066657Possibly a fitRecruiting

Study of MRG007 for advanced solid tumors

Locally Advanced or Metastatic Solid TumorsColorectal CancerGastric CancerPancreatic Cancer

Part of Cancer, Digestive system, Hormones & metabolism clinical trials.

This trial tests a new drug called MRG007 for people with advanced solid tumors that haven't responded to other treatments. The drug targets a protein called CDH17 on cancer cells; you need a tumor sample to check for it.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
572 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be willing to sign an informed consent form and follow the study plan.
  • Your doctor expects you to live at least 3 more months.
  • You need a tumor sample to test for CDH17, or you must be willing to have a biopsy to get one.
  • You must have advanced or metastatic cancer that has not responded to standard treatments, you couldn't tolerate them, or there are no standard options left.
  • You need to have at least one tumor that can be measured on a scan.
  • Your daily activity level must be fairly good (able to take care of yourself and do light work).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06242470Recruiting· Phase 1
Study of MGC026 for advanced solid tumors

This trial tests a new drug called MGC026 that targets a protein called B7-H3 on cancer cells, aiming to shrink or slow different advanced solid tumors. It is an early-phase study to find the right dose and check safety.

Los Angeles, California
NCT06751329Recruiting· Phase 1/Phase 2
Study of DM002 for advanced solid tumors

This trial tests a new drug called DM002 for people with advanced solid tumors that have not responded to standard treatments. The drug targets two proteins (MUC1 and HER3) found on some cancer cells, and may help shrink tumors or slow their growth.

San Francisco, California
NCT06625593Recruiting· Phase 1
Study of BG-C137 for advanced solid tumors

This trial tests a new drug called BG-C137 for people with advanced solid tumors that have stopped responding to other treatments. The drug targets a protein called FGFR2b found on some cancer cells, aiming to deliver a therapy directly to the tumor.

Los Angeles, California
NCT07737600Not yet recruiting· Phase 1/Phase 2
Study of MRG007 for advanced colorectal cancer

This trial tests a new drug called MRG007 combined with other treatments for people with advanced colorectal cancer that cannot be removed by surgery or has spread. It aims to see if the combination is safe and effective.

Beijing, Beijing Municipality
NCT07093970Recruiting· Phase 1/Phase 2
MRG006A for advanced solid tumors

This trial tests a new drug, MRG006A, for people with advanced solid tumors, especially liver cancer. It aims to see if the drug is safe and effective by targeting a protein called GPC3 found on some cancer cells.

Beijing, Beijing Municipality
NCT07479485Recruiting· Phase 1/Phase 2
MRG006A combo for advanced liver cancer

This trial tests a new drug combination called MRG006A for people with advanced liver cancer (hepatocellular carcinoma) that cannot be removed by surgery or treated with local therapies. The goal is to see if it helps shrink tumors or slow cancer growth.

Beijing, Beijing Municipality

Hear when a new Locally Advanced or Metastatic Solid Tumors trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.