A study of a new heart valve for people too sick for surgery
Part of Heart & circulation clinical trials.
This study is testing a new valve device (JenaValve Trilogy) that can be placed without open-heart surgery. It may be an option for people whose heart team says regular valve replacement surgery is too risky.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your heart team has decided that regular open-heart valve surgery is too risky for you.
- You are 18 years old or older.
- Your aortic valve and surrounding blood vessels are shaped correctly for this special valve device.
- You do not have a large aneurysm (ballooning) or a thick, unstable ulcer in the main artery coming out of your heart.
- You are not allergic to nickel, titanium, or the blood thinners used during the procedure, and you do not have a current heart infection.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study is testing a new type of heart valve (Navitor or Navitor Vision) for people with aortic stenosis. The valve is placed without open-heart surgery, and the goal is to see how well it works in a real-world setting. If you've already been recommended for this procedure by your heart team, you may be able to join.
This study tests a new, less invasive device called J-Valve for people with severe aortic regurgitation (a leaky aortic valve). It is placed through a tube in the leg artery, avoiding open-heart surgery, and may help those who are at high risk for surgery.
This trial tests a new device to treat a leaking aortic valve in people who already have a left ventricular assist device (LVAD). The goal is to fix the leak without open-heart surgery, which may improve how well the LVAD works and reduce symptoms.
This study is for people with a severe leaking aortic valve (aortic regurgitation) who are too high-risk for open-heart surgery. It tracks how well a less-invasive valve replacement (TAVI) using the JenaValve or J-Valve works for them.
This study is testing a new, less invasive heart valve system (TaurusTrio) for people with severe aortic regurgitation (a leaky aortic valve) who cannot have open-heart surgery. It aims to see if the valve is safe and works well to improve symptoms.
This trial compares a new catheter-based valve (J-Valve) with open-heart surgery for people with severe aortic regurgitation, a condition where the aortic valve doesn't close tightly. It aims to see which treatment is safer and more effective.
Hear when a new Aortic Regurgitation Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.