Testing BNT314 with pumitamig and chemo for advanced colorectal cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests a new combination of drugs (BNT314 and pumitamig) plus chemotherapy for people with advanced colorectal cancer that has not responded to prior treatments. The goal is to see if this combination is safe and helps shrink or control the cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced colorectal cancer that cannot be removed by surgery.
- Your tumor is not MSI-high or dMMR type (a specific genetic feature).
- You have had at least 2 prior lines of treatment for metastatic cancer and it has continued to grow.
- You can provide a tumor sample from a recent biopsy or an archived sample less than 2 years old.
- You are in good enough physical condition to be up and about (ECOG score 0 or 1).
- You have not had prior treatment with certain targeted therapies or immunotherapies listed in the trial.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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