Clin2
NCT07079696Worth exploringNot yet recruiting

Retinoic acid for autism with 15q11-13 duplication

Dup15q SyndromeAutism Spectrum DisorderTherapyAll-trans Retinoic Acid

Treatments studied

Part of Mental health clinical trials.

This study tests a medicine (all-trans retinoic acid) for children with autism who also have a specific genetic change (15q11-13 duplication). The goal is to see if it can help with autism symptoms.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
90 people
Ages
3 years to 7 years
Study type
Interventional

Who can take part

  • Your child must have a formal autism diagnosis (using DSM-5) from doctors.
  • A genetic test must show a specific chromosome change (15q11-13 duplication) that involves the UBE3A gene.
  • No infections (like colds or ongoing infections) in the past 3 months.
  • No seizures (fits) in the past 6 months.
  • No vitamin A or mineral supplements taken in the past month.
  • No chronic health issues like liver, kidney, or thyroid problems.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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