Clin2
NCT07080307Possibly a fitNot yet recruiting

Artificial intelligence predicts response to steroid injection for sciatica

SciaticaLow Back PainLumbar Spinal StenosisRadiculopathyLumbar Disc Herniation

Part of Bones, joints & muscles, Brain & nervous system, Pain clinical trials.

This study uses artificial intelligence to predict how well a patient with sciatica will respond to a steroid injection in the spine. It aims to help doctors personalize treatment and improve outcomes for people with nerve-related back and leg pain.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
1,500 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You must be 18 years or older.
  • You must have sciatica symptoms that match a specific nerve root (L4, L5, or S1) in your lower back.
  • Your symptoms must have lasted at least 3 months and not improved with usual care.
  • You must be scheduled to receive a steroid injection into the spine (called a transforaminal epidural steroid injection).
  • You cannot be pregnant, have a bleeding disorder, a history of allergic reactions to the injected substances, or major psychiatric illness.
  • You cannot have had an epidural steroid injection within the last 3 months or be on systemic steroids.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07367191Not yet recruiting
Pain relief after steroid injection for herniated disc

This study looks at how pain relief from a targeted steroid injection in the lower back changes over time, and whether early pain changes can predict long-term success. It may help doctors better plan treatments for people with herniated discs.

Istanbul
NCT07612982Not yet recruiting
Comparing two injection methods for spinal stenosis pain

This study compares two ways of giving a steroid injection into the lower back to relieve pain from lumbar spinal stenosis (a condition where the spinal canal narrows and presses on nerves). It may help you if you've tried other treatments without relief and you're experiencing leg pain when walking.

Istanbul, Pendik
NCT04540068Recruiting
Predicting whether a sciatica procedure will work

This study looks for ways to predict how well a specific sciatica procedure (TEI) will help. If you have one-sided nerve pain from the low back, the trial may help personalize treatment so you’re less likely to go through ineffective care.

Haarlem
NCT07762170Recruiting· Phase 4
Steroid injections for back and pelvic pain

This study is testing how well and how safely steroid injections work for different types of back pain. If you join, you'll receive the injection as part of your care and fill out surveys about your pain and ability to do daily activities before and after.

Thornhill, Ontario
NCT07828132Not yet recruiting
Emotion awareness and steroid injection outcomes for low back pain

This study looks at how a person's ability to recognize and express emotions (called alexithymia) may affect how well they respond to a steroid injection for low back pain. The injection is given in the lower back to reduce pain and inflammation, and the study hopes to see if emotional awareness plays a role in treatment success.

NCT07813988Not yet recruiting· Phase 4
Comparing three steroid injection methods for leg pain

This study tests three different ways to give a steroid injection near the spine to treat leg pain caused by a herniated disc. It may help you avoid surgery by reducing pain and improving function.

Banhā, Qalyubia Governorate

Hear when a new Sciatica trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.