Testing Two Immunotherapy Drugs for Advanced Head and Neck Cancer
Treatments studied
Part of Cancer clinical trials.
This trial tests two new immunotherapy drugs, iparomlimab and tuvonralimab, for people with head and neck squamous cell cancer that has spread or come back after at least 2 prior treatments. The goal is to see if this combination can shrink or slow the cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have head and neck squamous cell cancer that started in the mouth, throat, voice box, or lower throat, and it has spread or come back after at least 2 previous treatments.
- You are able to do light activities (like walking) and are expected to live at least 12 weeks.
- Your blood counts, liver, kidney, and heart function are within a certain healthy range.
- You have not had a CTLA-4 inhibitor (like ipilimumab) before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a combination of two immunotherapy drugs (Iparomlimab and Tuvonralimab) with low-dose radiation and chemotherapy for advanced head and neck cancer. It aims to see if this approach can help patients who have not had prior treatment for their cancer.
This trial tests a new combination of two immunotherapy drugs (called iparomlimab and tuvonralimab), with or without chemotherapy, for head and neck squamous cell carcinoma that has returned or spread after previous treatment. The goal is to see if this combination can help people with this cancer live longer with fewer side effects.
This trial tests a new combination of immunotherapy drugs plus radiation and chemotherapy for people with large, hard-to-treat head and neck cancer that hasn't spread far. It aims to see if this approach can shrink tumors and improve outcomes.
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