Clin2
NCT07095309Possibly a fitNot yet recruiting

Testing artesunate before surgery for colorectal cancer

Stage II/III Colon CancerBowel Cancer

Treatments studied

Part of Cancer, Digestive system clinical trials.

This trial tests if giving artesunate before surgery is safe and helps treat stage II or III colorectal cancer. You might benefit if you are scheduled for surgery and have not been recommended chemotherapy or radiation before the operation.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
120 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • You must have stage II or III colorectal cancer that can be removed with surgery.
  • You should not need chemotherapy or radiation before surgery.
  • You must be in generally good health (able to care for yourself).
  • Your blood counts, kidney, and liver function must be within acceptable ranges.
  • If you could become pregnant or get someone pregnant, you must use effective birth control during and 6 weeks after treatment.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07503639Not yet recruiting· Phase 2
Pre-surgery therapy study for advanced colorectal cancer

This trial tests giving treatment before surgery for stage II or III colorectal cancer that has not spread. It aims to see if this approach can improve outcomes for patients who have not had prior cancer therapy.

NCT06899477Not yet recruiting· Phase 3
Chemo before surgery for colon cancer

This trial tests whether giving chemotherapy before surgery can improve outcomes for people with colon cancer that has grown into nearby tissue or lymph nodes but hasn't spread to other organs. It is for patients whose tumors are mismatch repair proficient (pMMR) or microsatellite stable (MSS).

Berlin
NCT05194878Recruiting· Phase 3
Before-surgery chemotherapy vs immediate surgery for colon cancer

This trial compares giving chemotherapy before surgery versus going straight to surgery for certain stage II/III colon cancers. It may help shrink the tumor and improve outcomes by testing which approach works best for high-risk cases.

Guangzhou, Guangdong
NCT06368141Recruiting· Phase 2
Chemo plus immunotherapy before surgery for colon cancer

This trial tests whether giving chemotherapy followed by an immunotherapy drug (a checkpoint inhibitor) before surgery helps shrink locally advanced colon cancer. It is for people with a specific tumor type (MSS and RAS mutation) who have not had prior treatment.

Shanghai, Shanghai Municipality
NCT05585814Recruiting· Phase 2
New chemo plus immunotherapy before rectal surgery

This trial tests a combination of chemo, a medicine that blocks blood vessel growth, and an immune checkpoint drug given before rectal cancer surgery. It’s for people with locally advanced rectal cancer without distant spread, to try to shrink the tumor and improve surgical results.

Shanghai
NCT06280495Recruiting· Phase 2/Phase 3
Targeted drugs plus chemo before surgery for colon cancer with liver spread

This trial tests whether adding two targeted drugs (serplulimab and bevacizumab) to standard chemotherapy before surgery can improve outcomes for people with colorectal cancer that has spread to the liver. It is for those whose cancer has certain genetic features and is considered resectable.

Guangzhou, Guangdong

Hear when a new Bowel Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.