Surfactant therapy for premature babies with breathing problems
Part of Lungs & breathing, Women’s health & pregnancy clinical trials.
This trial tests whether giving surfactant (a substance that helps lungs stay open) to premature babies with Respiratory Distress Syndrome (RDS) through a mask on the throat (supraglottic airway) is safe and effective. It may be an option for babies who need extra oxygen but are not on a breathing tube.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Born at this hospital before 34 weeks of pregnancy
- Birth weight of at least 1.6 pounds (750 grams)
- Less than 48 hours old
- Diagnosed with Respiratory Distress Syndrome (RDS), confirmed by chest x-ray or lung ultrasound unless immediate treatment is needed
- On non-invasive breathing support (like CPAP or NIPPV) and needs extra oxygen (more than 30% oxygen)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at different ways doctors give a life-saving medication called surfactant to premature babies who are struggling to breathe. Researchers want to understand which delivery methods work best and help improve care.
This trial uses a lung ultrasound score, a type of ultrasound, to decide when to give surfactant (a medicine that helps lungs work) to premature babies born between 27 and 35 weeks of pregnancy. It aims to reduce the need for more breathing support and avoid side effects.
This trial is studying whether giving a lung “surfactant” medicine through a thin tube (called LISA) helps very premature babies with breathing problems. It aims to see if this approach improves care for babies born around 24 to 30 weeks gestation who still need oxygen support.
This trial tests if giving surfactant (a natural substance that helps lungs stay open) through a special airway device can help late preterm and early term infants with breathing problems. The goal is to see if this approach works better than current methods without needing a breathing tube.
This study compares two ways of giving surfactant (a natural substance that helps lungs stay open) to premature babies who need extra breathing support. It aims to find which method works better and is safer for infants born at 29 to 36 weeks.
This Phase 3 trial tests whether InfasurfAero™ (a type of surfactant given as aerosol) works better than a sham treatment in preterm babies with respiratory distress syndrome (RDS). It aims to improve breathing in the first hours of life for babies who need CPAP.
Hear when a new Respiratory Distress Syndrome in Premature Infant trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.