Blinatumomab and donor cells after transplant for high-risk B-ALL
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests whether giving two drugs—blinatumomab (an immunotherapy) and donor lymphocyte infusions (white blood cells from your donor)—can help prevent leukemia from coming back after a stem cell transplant for high-risk B-ALL. It is for people who are in remission with no sign of leukemia cells.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 14 and 65 years old.
- You have high-risk Philadelphia chromosome-negative B-cell acute lymphoblastic leukemia (B-ALL) and have already received a stem cell transplant from a donor.
- You are currently in remission (no leukemia cells found in your bone marrow) and have no detectable minimal residual disease (MRD).
- You do not have active graft-versus-host disease (GVHD) or a history of severe GVHD.
- Your liver, kidney, and heart function are adequate (based on blood tests and heart scan).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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