Blinatumomab before stem cell transplant for high-risk B-ALL
Treatments studied
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This trial tests giving a drug called blinatumomab before a stem cell transplant for people with high-risk B-cell acute lymphoblastic leukemia (B-ALL) that is in remission and has no detectable cancer cells. The goal is to see if this extra treatment helps prevent the leukemia from coming back after transplant.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have B-cell acute lymphoblastic leukemia (B-ALL) with high-risk features.
- You are between 18 and 65 years old.
- Your leukemia is in complete remission and has no detectable cancer cells (MRD-negative).
- You have a suitable stem cell donor (sibling, family member, or unrelated donor).
- Your heart, liver, and kidneys are working well enough.
- You have not had blinatumomab or CAR T-cell therapy before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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