Testing ways to check heart arteries before valve replacement
Part of Heart & circulation clinical trials.
This trial compares different methods to evaluate coronary artery disease in patients planning to have a transcatheter aortic valve replacement (TAVR) for severe aortic stenosis. The goal is to find out if a less invasive approach is as safe and effective as the standard one.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have severe aortic valve narrowing (aortic stenosis) and your doctor has recommended a procedure to fix it.
- You are scheduled to have a transcatheter aortic valve replacement (TAVR).
- You are willing and able to provide signed consent to participate.
- You do not have cardiogenic shock (a sudden, severe drop in blood flow).
- You do not have severe kidney disease (estimated GFR below 30).
- You are expected to live at least one more year (no other life-limiting illness like advanced cancer).
- You are not pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a less invasive heart valve replacement (TAVR) for people with a leaky aortic valve (aortic regurgitation). It uses ultrasound guidance to place the new valve, which may offer a treatment option for those who cannot have open-heart surgery.
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This study checks whether special heart tests can better understand “in-between” blocked heart arteries before and after TAVI (a valve replacement done through a catheter). It may help doctors choose the safest, most accurate treatment when coronary artery disease is unclear.
This trial compares two approaches for replacing a tight aortic heart valve (TAVI) through a leg artery: doing it with or without a routine check of your heart's arteries (coronary angiogram). If you have severe aortic stenosis and are scheduled for TAVI, this study helps find out whether skipping the artery check is safe and effective.
This trial studies whether a new through-the-blood-vessel heart valve (TAVR) is safe and works well for people with severe aortic stenosis who are too risky for traditional surgery. If you qualify, you would be closely followed to check your symptoms and valve function over time.
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