Testing ways to check heart arteries before valve replacement
Part of Heart & circulation clinical trials.
This trial compares different methods to evaluate coronary artery disease in patients planning to have a transcatheter aortic valve replacement (TAVR) for severe aortic stenosis. The goal is to find out if a less invasive approach is as safe and effective as the standard one.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have severe aortic valve narrowing (aortic stenosis) and your doctor has recommended a procedure to fix it.
- You are scheduled to have a transcatheter aortic valve replacement (TAVR).
- You are willing and able to provide signed consent to participate.
- You do not have cardiogenic shock (a sudden, severe drop in blood flow).
- You do not have severe kidney disease (estimated GFR below 30).
- You are expected to live at least one more year (no other life-limiting illness like advanced cancer).
- You are not pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests different ways to check for blocked heart arteries in patients getting a new aortic valve through a tube in the leg. It aims to find the best approach to guide treatment.
This trial compares two approaches for replacing a tight aortic heart valve (TAVI) through a leg artery: doing it with or without a routine check of your heart's arteries (coronary angiogram). If you have severe aortic stenosis and are scheduled for TAVI, this study helps find out whether skipping the artery check is safe and effective.
This trial studies whether a new through-the-blood-vessel heart valve (TAVR) is safe and works well for people with severe aortic stenosis who are too risky for traditional surgery. If you qualify, you would be closely followed to check your symptoms and valve function over time.
This study checks whether an “investigational” transcatheter aortic valve is safe and works well for people with severe, calcified aortic stenosis (a stiff, narrowed heart valve). It may help improve valve function and symptoms, but you must meet specific heart, scan, and health-status requirements.
This trial studies heart imaging tests (from multiple types of scans) for people who have a narrowed aortic valve and are being checked for a valve replacement through the catheter (often called TAVI). It may help doctors better plan the procedure and understand heart function before treatment.
This trial studies people with severe aortic valve disease who will receive a catheter-based valve replacement (TAVR). It aims to check how well this approach works for fixing a narrowed or leaky aortic valve, and to monitor outcomes afterward.
Hear when a new Aortic Valve Stenosis and Insufficiency trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.