Short versus long radiation schedule for advanced rectal cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This study compares two different schedules of radiation (a short course versus a longer course) followed by standard chemotherapy and immunotherapy for advanced rectal cancer. It aims to see which approach works best to shrink the tumor before surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have a type of rectal cancer called locally advanced adenocarcinoma that is pMMR or MSS (this means it may respond well to immunotherapy).
- You have not had any prior treatment for your rectal cancer (like surgery, radiation, or chemotherapy).
- Your tumor is located no more than 10 cm (about 4 inches) from your anal opening.
- You are in good general health (able to do daily activities without help, with good blood, liver, and kidney function).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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