Belumosudil for children with chronic GVHD

This trial tests a pill called belumosudil to see if it can help people with chronic graft-versus-host disease (a common complication after a stem cell transplant where donor cells attack your body). It is for patients who have symptoms but are not yet on strong immune-suppressing drugs.

This study tests a new medicine called belumosudil for people who have chronic graft-versus-host disease (cGVHD) that has not improved with at least two earlier treatments. It compares belumosudil to other available treatments to see which works better and is safer.

This study tests an oral medication called belumosudil for people who have chronic graft-versus-host disease (cGVHD) after a stem cell transplant. It aims to see how safe the drug is. You may qualify if you have already tried at least two other treatments and are currently on a stable steroid dose.

This trial tests whether crushing belumosudil tablets changes how the drug works in people with chronic graft-versus-host-disease (GVHD), a complication after a stem cell transplant. It helps doctors know if taking crushed pills is as effective as whole tablets.

This study compares how the body absorbs a drug called belumosudil when given as a liquid versus a tablet. It aims to see if the two forms are similar, which could help decide the best way to give the drug in the future.

This Phase 2 study tests belumosudil to treat or prevent bronchiolitis obliterans (BOS), a lung complication that can happen after a stem cell transplant. If you qualify, you would be checked closely with breathing tests and scans, and watched for safety and whether lung function improves or stays stable.