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NCT07125417Possibly a fitRecruiting

Blood thinner comparison after left atrial appendage closure

Nonvalvular Atrial FibrillationAspirinNon-Antithrombotic TherapyHigh Bleeding RiskLeft Atrial Appendage Closure

Part of Heart & circulation clinical trials.

This study compares two approaches after a left atrial appendage closure (LAAC) procedure: taking no blood thinner versus taking just one antiplatelet medication. It aims to see which option is safer for people with atrial fibrillation who are at risk for bleeding.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
500 people
Ages
Any age
Study type
Interventional

Who can take part

  • You have atrial fibrillation that is not caused by a heart valve problem.
  • You have a CHA2DS2-VA score of 2 or higher (a measure of stroke risk).
  • You have already had a successful left atrial appendage closure with the Watchman FLX Pro device.
  • You are not already on blood thinners for reasons other than atrial fibrillation.
  • You have not had a stroke, heart attack, or major surgery within the last 30 days.
  • You are not pregnant, breastfeeding, or planning to become pregnant.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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