Comparing two procedures to close the left atrial appendage in atrial fibrillation
Part of Heart & circulation clinical trials.
This study compares two ways of closing a small pouch in the heart (the left atrial appendage) to help prevent strokes in people with atrial fibrillation (an irregular heartbeat). One method is less invasive, and the study aims to see if it is as safe and effective as the standard approach.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 85 years old.
- You have atrial fibrillation that is not caused by a heart valve problem.
- Your risk of stroke is high (CHA2DS2-VASc score of 2 or more) and your risk of bleeding is also high (HAS-BLED score of 3 or more), or you cannot take blood thinners long-term.
- You are expected to live at least one more year.
- You do not have blood clots in the heart, severe kidney or liver problems, very low platelet counts, or severe heart failure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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