Stepwise treatment for persistent atrial fibrillation
Part of Heart & circulation clinical trials.
This study tests a stepwise treatment plan for people with persistent atrial fibrillation (a long-lasting irregular heartbeat) who also have an enlarged left atrium. It aims to see if a medication called amiodarone plus a cardioversion procedure can help restore normal rhythm.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have persistent atrial fibrillation (a heart rhythm problem that lasts more than a week) and your left atrium (a heart chamber) is enlarged (40-50 mm measured by ultrasound).
- You are between 18 and 80 years old.
- You are willing to take amiodarone (a medication) and undergo cardioversion (a procedure to restore normal heart rhythm).
- You are not pregnant, breastfeeding, or planning pregnancy in the next 2 years.
- You do not have serious kidney, liver, thyroid, or heart problems, or a known allergy to amiodarone or iodine.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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