Testing amiodarone before heart shock therapy for persistent atrial fibrillation
Treatments studied
Part of Heart & circulation clinical trials.
This trial is testing whether giving amiodarone (a heart-rhythm medicine) before an electrical cardioversion can help restore normal heart rhythm better in people with persistent atrial fibrillation. The goal is to see if the medicine makes the procedure more likely to succeed and reduces the chance of the irregular rhythm returning.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have had persistent atrial fibrillation (a type of irregular heart rhythm) for at least 7 days.
- You are scheduled to have an elective (non-urgent) electrical cardioversion (a procedure to shock your heart back to normal rhythm).
- You have not taken amiodarone in the last 30 days or other heart-rhythm medicines in the last 7 days.
- You do not have severe heart failure, a very weak heart pump, serious thyroid or liver disease, or certain valve problems in your heart.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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