Clin2
NCT07130786Possibly a fitRecruiting

Preventing seizures with medication for brain tumors in movement area

SeizuresPrimary Motor CortexBrain Metastases From Non-small Cell Lung Cancer (NSCLC)Brain Metastases, AdultBrain Metastases From Extra-cranial Solid Tumors

Treatments studied

Part of Brain & nervous system, Cancer clinical trials.

This study tests whether giving a seizure medication (levetiracetam) to people with brain tumors in the movement area can prevent seizures. It compares taking the medication to not taking it, starting before any seizure occurs.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
150 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must have a solid cancer that has spread to the brain, with at least one tumor in the movement area that is at least half a centimeter wide.
  • You must be 18 years or older.
  • You must be able to care for yourself (performance status 60 or higher).
  • You must have had no seizures before (this study is for people who have never had a seizure).
  • You must not be allergic to the study drug levetiracetam (Keppra).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05897658Not yet recruiting· Phase 3
Levetiracetam to prevent seizures after brain tumor surgery

This trial tests whether taking levetiracetam (a medicine used to prevent seizures) around the time of brain tumor surgery can reduce the chance of postoperative seizures. It may help people who are having surgery in the brain area where seizures are a known risk.

NCT06442748Recruiting· Phase 3
Short vs long seizure medicine in brain tumor patients

This study compares stopping seizure medicine (levetiracetam) after 6 months versus continuing it longer for people with primary brain tumors. It aims to find out if it is safe to stop the medication sooner and may help you avoid long-term side effects.

Udupi, Karnataka
NCT07721272Not yet recruiting· Early Phase 1
Brain During Surgery: Thinking and Medication Study

This study tests whether giving a drug that affects brain chemistry during brain surgery can improve thinking and attention for people with essential tremor or epilepsy. If you qualify, you might receive the drug or a placebo during your electrode placement surgery to see how it affects your cognition.

Dallas, Texas
NCT07239115Recruiting· Phase 3
Levetiracetam to prevent seizures after brain tumor surgery

This trial tests whether the drug levetiracetam can prevent seizures in people who have brain tumor surgery. If you are having surgery to remove a brain tumor and have never had a seizure, this study may help keep you from having one after the operation.

Beijing
NCT03048084Recruiting· Phase 4
Testing seizure medicines after a first seizure in brain tumors

This trial studies which seizure medicine works best for adults who recently had their first seizure caused by certain brain tumors. It may help reduce seizures and improve daily functioning while choosing the right medicine after the first episode.

Amsterdam
NCT07758062Not yet recruiting· Phase 2
Levetiracetam with standard chemo-radiation for hypoxic glioblastoma

This trial tests whether adding an extended-release seizure medication (levetiracetam) to the standard treatment plan (surgery followed by radiation and chemotherapy) can improve outcomes for people with a specific type of brain tumor called glioblastoma, especially when the tumor shows signs of low oxygen levels (hypoxia).

Tianjin, Tianjin Municipality

Hear when a new Seizures trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.