Clinical trials
Seizures clinical trials
Below are recruiting seizures clinical trials, each written for real people, not researchers. We’re tracking 104 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03822741Recruiting
Seizure causes and treatments in newborns and infants
This study looks at what causes certain serious seizures that start early in life, and how to treat them. It may help doctors better match treatments to the seizure cause in newborns and young infants.
Shanghai, Shanghai MunicipalityAges Up to 1 year - NCT07219407RecruitingPhase 2
Long-term safety study of RAP-219 for focal seizures
This study tests the long-term safety and effectiveness of RAP-219, an investigative medication for focal epilepsy. It is for people who already completed an earlier study of RAP-219, have a type of epilepsy that doesn't respond to standard medicines, and use a surgically implanted brain device (RNS system) to help manage seizures.
Boise, IdahoAges 18–70 - NCT06657378Recruiting
Safety study of Fycompa injection for certain seizures
This study looks at the safety of Fycompa given as an injection for people with partial-onset seizures (seizures that start in one part of the brain) or primary generalized tonic-clonic seizures (seizures that affect both sides of the brain from the start). It includes anyone receiving Fycompa injection for the first time in everyday medical care.
TokyoAges 4 years+ - NCT05121324RecruitingPhase 3
Tested higher-dose seizure medicine for children during EMS care
This trial studies the best dose of a seizure medicine for children who are actively seizing while emergency medical teams are treating them. It may help EMS crews give safer, more effective treatment during transport.
Tucson, ArizonaAges 6 months–13 years - NCT05610085RecruitingPhase 2
Levetiracetam for newborn seizures: dose-finding study
This trial studies how to give levetiracetam to newborn babies with seizures. It’s trying to find a safe dose and see if it can help control seizures in early life.
San Diego, CaliforniaAges Up to 1 month - NCT05724719Recruiting
Study brain signals after a first unprovoked seizure
This study looks at people ages 18 to 65 after they have a first seizure that is not clearly triggered. It also compares them with healthy volunteers to better understand what might predict whether seizures come back.
Halifax, Nova ScotiaAges 18–65 - NCT07473648Recruiting
A trial of ECT and magnetic seizure therapy for mood disorders
This study compares two types of brain stimulation treatments—electroconvulsive therapy (ECT) and magnetic seizure therapy (MST)—to see which works better for people with certain mental health conditions. It may be an option if you have a mood disorder or vision problems that could be helped by these treatments.
Hefei, AnhuiAges 12–80 - NCT07130786RecruitingPhase 2
Preventing seizures with medication for brain tumors in movement area
This study tests whether giving a seizure medication (levetiracetam) to people with brain tumors in the movement area can prevent seizures. It compares taking the medication to not taking it, starting before any seizure occurs.
Boston, MassachusettsAges 18 years+ - NCT07012148RecruitingEarly Phase 1
Seizure forecasting device for temporal lobe epilepsy
This study tests a small device placed under the scalp that may help predict when seizures are likely to happen, using EEG (brain wave) readings. It is designed for people with temporal lobe epilepsy to improve seizure management and safety.
Scottsdale, ArizonaAges 18–75 - NCT06952764Enrolling by invitation
ECLIPSE: Tracking epilepsy cycles to predict seizures
This trial tests if tracking your brain activity with an implanted device can help predict when seizures might happen. It is for adults who have seizures despite medication and already have the RNS System implanted.
San Francisco, CaliforniaAges 18 years+ - NCT06700356Recruiting
Can a brain stimulator detect seizures in the thalamus?
This study tests whether a special brain stimulator (already implanted in some people with epilepsy) can detect seizures in the thalamus. It may help improve seizure monitoring without extra surgery.
Rochester, MinnesotaAges 18 years+ - NCT06388707RecruitingPhase 1/Phase 2
Ultrasound therapy for drug-resistant temporal lobe epilepsy
This study tests if a new, non-invasive ultrasound treatment can safely reduce seizures in people whose seizures start in the temporal lobe and have not been controlled by at least two anti-epileptic drugs. The ultrasound is delivered through the scalp to gently stimulate the brain area where the seizures begin.
Palo Alto, CaliforniaAges 18 years+ - NCT07594119RecruitingPhase 3
Testing RAP-219 to reduce seizures in focal epilepsy
This study tests a new medication called RAP-219 to see if it can reduce seizure frequency in adults with focal epilepsy (seizures starting in one area of the brain). You'll take the medication alongside your current seizure drugs and track your seizures daily using an app.
Huntsville, AlabamaAges 18–75 - NCT04076449Recruiting
MRI measurements for epilepsy from a single brain blood vessel lump
This study uses special MRI scans to measure brain changes in people whose seizures are related to one cerebral cavernous malformation (a type of abnormal blood vessel in the brain). It aims to find a measurable “biomarker” from MRI that may help understand the epilepsy and the brain structure around it.
Beijing, Beijing MunicipalityAges 18–70 - NCT07793396Recruiting
Eslicarbazepine study for adults with partial-onset seizures
This study tests a medication called eslicarbazepine for adults who have partial-onset seizures. It may help people who are newly diagnosed or who have not had good results with two common seizure medicines, carbamazepine or oxcarbazepine.
Lahore, Punjab ProvinceAges 18 years+ - NCT07747324RecruitingPhase 1/Phase 2
Testing ayahuasca for psychogenic non-epileptic seizures
This trial tests whether a single dose of ayahuasca, a plant-based brew, can reduce psychogenic non-epileptic seizures (PNES). It may help if you are willing to stop psychiatric medications temporarily and have no other serious mental health conditions.
Ribeirão Preto, São PauloAges 18–60 - NCT05725174Recruiting
Study seizure signals using quick, non-invasive breath tests
This study looks for “volatile” (gaseous) body signals from breath to help identify seizure events. If you were recently admitted for seizure diagnosis, you may be asked to provide breath samples in a non-invasive way.
London, BuckinghamshireAges 18 years+ - NCT07563881RecruitingPhase 3
Testing RAP-219 for Focal Seizure Control in Adults
This study tests whether a new medication called RAP-219 can help adults with focal seizures (seizures that start in one area of the brain) control their seizures better. You would take this medication alongside your current seizure drugs for about 12 weeks.
Palmdale, CaliforniaAges 18–75 - NCT07533773Recruiting
Brain Activity Changes After Depression Treatment
This study measures how brain activity in specific regions changes after you receive electroconvulsive therapy (ECT) or magnetic seizure therapy (MST) for severe depression. Researchers use a non-invasive headband to monitor blood flow in your brain before and after treatment to better understand how these therapies work.
Hefei, AnhuiAges 12–65 - NCT06814665Recruiting
Better diagnosis and care after a first seizure
This study aims to improve how doctors diagnose and treat people after their first suspected seizure. It may help if you've had a recent event that might have been a seizure and haven't been diagnosed with epilepsy before.
BergenAges Any age - NCT06836687Recruiting
How a new epilepsy definition affects diagnosis after a first seizure
This study looks at how the new 2014 definition of epilepsy from the ILAE affects diagnosis after a first seizure. It is for adults who have had their very first seizure and can give consent.
Marburg, HesseAges 18 years+ - NCT07318870RecruitingPhase 2
Probenecid for reducing seizure clusters during hospital epilepsy monitoring
This trial tests whether a drug called probenecid can help reduce the number of seizures that happen in a cluster during a hospital stay when your seizure medications are being reduced to record your seizures. The goal is to see if giving probenecid can make the monitoring period safer and more effective for people with focal epilepsy being evaluated for surgery.
ParisAges 6–50 - NCT07287163Enrolling by invitationPhase 3
Long-term study of vormatrigine for epilepsy
This trial is for adults with epilepsy who have already taken vormatrigine in a previous study or through a special access program. It aims to collect ongoing safety and effectiveness information.
Miami, FloridaAges 18–85 - NCT07233239RecruitingPhase 1
CBD liquid for focal epilepsy seizures
This trial tests a new cannabidiol (CBD) liquid medicine for people with focal epilepsy (seizures that start in one part of the brain). It looks at whether the medication can help reduce seizures when added to your current seizure medications.
Phoenix, ArizonaAges 12–75
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Seizures trials by city
Studies with a site in or near these metro areas.
Seizures trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for seizures?
- Yes. Clin2 currently lists 104 recruiting seizures studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a seizures trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a seizures trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.