Clinical trials
Seizures clinical trials
Below are recruiting seizures clinical trials, each written for real people, not researchers. We’re tracking 110 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03822741Recruiting
Seizure causes and treatments in newborns and infants
This study looks at what causes certain serious seizures that start early in life, and how to treat them. It may help doctors better match treatments to the seizure cause in newborns and young infants.
Shanghai, Shanghai MunicipalityAges Up to 1 year - NCT05121324RecruitingPhase 3
Tested higher-dose seizure medicine for children during EMS care
This trial studies the best dose of a seizure medicine for children who are actively seizing while emergency medical teams are treating them. It may help EMS crews give safer, more effective treatment during transport.
Tucson, ArizonaAges 6 months–13 years - NCT06657378Recruiting
Safety study of Fycompa injection for certain seizures
This study looks at the safety of Fycompa given as an injection for people with partial-onset seizures (seizures that start in one part of the brain) or primary generalized tonic-clonic seizures (seizures that affect both sides of the brain from the start). It includes anyone receiving Fycompa injection for the first time in everyday medical care.
TokyoAges 4 years+ - NCT07219407RecruitingPhase 2
Long-term safety study of RAP-219 for focal seizures
This study tests the long-term safety and effectiveness of RAP-219, an investigative medication for focal epilepsy. It is for people who already completed an earlier study of RAP-219, have a type of epilepsy that doesn't respond to standard medicines, and use a surgically implanted brain device (RNS system) to help manage seizures.
Boise, IdahoAges 18–70 - NCT07473648Recruiting
A trial of ECT and magnetic seizure therapy for mood disorders
This study compares two types of brain stimulation treatments—electroconvulsive therapy (ECT) and magnetic seizure therapy (MST)—to see which works better for people with certain mental health conditions. It may be an option if you have a mood disorder or vision problems that could be helped by these treatments.
Hefei, AnhuiAges 12–80 - NCT06700356Recruiting
Can a brain stimulator detect seizures in the thalamus?
This study tests whether a special brain stimulator (already implanted in some people with epilepsy) can detect seizures in the thalamus. It may help improve seizure monitoring without extra surgery.
Rochester, MinnesotaAges 18 years+ - NCT05610085RecruitingPhase 2
Levetiracetam for newborn seizures: dose-finding study
This trial studies how to give levetiracetam to newborn babies with seizures. It’s trying to find a safe dose and see if it can help control seizures in early life.
San Diego, CaliforniaAges Up to 1 month - NCT05724719Recruiting
Study brain signals after a first unprovoked seizure
This study looks at people ages 18 to 65 after they have a first seizure that is not clearly triggered. It also compares them with healthy volunteers to better understand what might predict whether seizures come back.
Halifax, Nova ScotiaAges 18–65 - NCT06388707RecruitingPhase 1/Phase 2
Ultrasound brain stimulation for drug-resistant epilepsy
This trial tests a low-intensity focused ultrasound device that aims to calm overactive brain areas causing seizures. It's for people whose seizures are not controlled by medication.
Palo Alto, CaliforniaAges 18 years+ - NCT06444126Recruiting
Study of fever seizures coming back and epilepsy risk
This study follows children who had their first seizure with a fever to see how often seizures come back and if they develop epilepsy. It helps doctors understand which children need extra monitoring.
Ho Chi Minh CityAges 1 month–8 years - NCT07130786RecruitingPhase 2
Preventing seizures with medication for brain tumors in movement area
This study tests whether giving a seizure medication (levetiracetam) to people with brain tumors in the movement area can prevent seizures. It compares taking the medication to not taking it, starting before any seizure occurs.
Boston, MassachusettsAges 18 years+ - NCT06952764Enrolling by invitation
ECLIPSE: Tracking epilepsy cycles to predict seizures
This trial tests if tracking your brain activity with an implanted device can help predict when seizures might happen. It is for adults who have seizures despite medication and already have the RNS System implanted.
San Francisco, CaliforniaAges 18 years+ - NCT07793396Recruiting
Eslicarbazepine study for adults with partial-onset seizures
This study tests a medication called eslicarbazepine for adults who have partial-onset seizures. It may help people who are newly diagnosed or who have not had good results with two common seizure medicines, carbamazepine or oxcarbazepine.
Lahore, Punjab ProvinceAges 18 years+ - NCT05077904RecruitingPhase 3
Staccato alprazolam study for prolonged seizures in teens and adults
This Phase 3 trial tests whether staccato alprazolam can reduce and manage “prolonged seizures” that happen repeatedly in people with epilepsy. It also checks safety—especially breathing and heart-related side effects—while participants continue their usual seizure medicines.
Phoenix, ArizonaAges 12 years+ - NCT06275685Recruiting
Forecasting seizures with a smart wearable
This study tests if a smart wristband called EmbracePlus can predict seizures. You wear the device and track your seizures to see if it can warn you ahead of time.
Boston, MassachusettsAges 6 years+ - NCT05076617Enrolling by invitationPhase 3
Testing a long-acting rescue seizure medicine for prolonged seizures
This Phase 3 study tests the safety and side effects of Staccato alprazolam for teens and adults (12+) who have certain types of long-lasting seizures. It may help people by offering a specific medicine option aimed at stopping prolonged seizure episodes under close medical study.
Phoenix, ArizonaAges 12 years+ - NCT07563881RecruitingPhase 3
Testing RAP-219 for Focal Seizure Control in Adults
This study tests whether a new medication called RAP-219 can help adults with focal seizures (seizures that start in one area of the brain) control their seizures better. You would take this medication alongside your current seizure drugs for about 12 weeks.
Palmdale, CaliforniaAges 18–75 - NCT06529029RecruitingPhase 2/Phase 3
Comparing new low-pulse ECT to standard ECT for depression
This trial tests a new type of seizure therapy (low amplitude pulse seizure therapy) against the standard ultra-brief right unilateral ECT for people with severe depression, including those with suicidal thoughts. The goal is to see which treatment works better.
Grand Rapids, MichiganAges 18–90 - NCT07239115RecruitingPhase 3
Levetiracetam to prevent seizures after brain tumor surgery
This trial tests whether the drug levetiracetam can prevent seizures in people who have brain tumor surgery. If you are having surgery to remove a brain tumor and have never had a seizure, this study may help keep you from having one after the operation.
BeijingAges 18–75 - NCT07747324RecruitingPhase 1/Phase 2
Testing ayahuasca for psychogenic non-epileptic seizures
This trial tests whether a single dose of ayahuasca, a plant-based brew, can reduce psychogenic non-epileptic seizures (PNES). It may help if you are willing to stop psychiatric medications temporarily and have no other serious mental health conditions.
Ribeirão Preto, São PauloAges 18–60 - NCT07594119RecruitingPhase 3
Testing RAP-219 to reduce seizures in focal epilepsy
This study tests a new medication called RAP-219 to see if it can reduce seizure frequency in adults with focal epilepsy (seizures starting in one area of the brain). You'll take the medication alongside your current seizure drugs and track your seizures daily using an app.
Bentonville, ArkansasAges 18–75 - NCT07287163Enrolling by invitationPhase 3
Long-term study of vormatrigine for epilepsy
This trial is for adults with epilepsy who have already taken vormatrigine in a previous study or through a special access program. It aims to collect ongoing safety and effectiveness information.
Miami, FloridaAges 18–85 - NCT05851391RecruitingPhase 2
Test drug treatment to stop hard-to-control seizures after cardiac arrest
This Phase 2 trial tests a medication strategy to stop “refractory status epilepticus,” a severe seizure condition that can happen after a cardiac arrest. It may help by reducing ongoing seizure activity after return of circulation in the ICU.
San Francisco, CaliforniaAges 18 years+ - NCT07533773Recruiting
Brain Activity Changes After Depression Treatment
This study measures how brain activity in specific regions changes after you receive electroconvulsive therapy (ECT) or magnetic seizure therapy (MST) for severe depression. Researchers use a non-invasive headband to monitor blood flow in your brain before and after treatment to better understand how these therapies work.
Hefei, AnhuiAges 12–65
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Seizures trials by city
Studies with a site in or near these metro areas.
Seizures trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for seizures?
- Yes. Clin2 currently lists 110 recruiting seizures studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a seizures trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a seizures trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.