Stem cells for liver failure without virus
Treatments studied
Part of Digestive system clinical trials.
This trial tests whether injecting special stem cells (called mesenchymal stem cells) can help people with a sudden worsening of chronic liver disease (called acute-on-chronic liver failure) who do not have a virus as the cause. It is for patients who are too sick for standard treatment but who cannot get a liver transplant right away.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- Your liver disease suddenly got worse and is not caused by a virus (like hepatitis B or C).
- Your liver is working very poorly (a MELD score over 18 or a similar high score).
- You do not have an active infection, bleeding, or cancer in or outside the liver.
- You do not have severe heart or lung disease or need strong medicines for very low blood pressure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether infusing stem cells (from a healthy donor) can help people with sudden liver failure that is not getting better with standard medicines and is not caused by viruses. It aims to improve liver function and possibly avoid the need for a transplant.
This trial tests whether a treatment called therapeutic plasma exchange (a process that filters your blood) can help improve the function of other organs in people with severe liver failure. It aims to see if this treatment leads to better outcomes and to find markers that predict who will benefit.
This early-phase study tests whether stem cells (called mesenchymal stem cells) are safe and can help people with a sudden, severe liver failure. You may qualify if your liver is failing quickly and you are not eligible for a transplant.
This trial tests whether stem cells from donated umbilical cords can help people with acute-on-chronic liver failure, a sudden worsening of chronic liver disease. The goal is to see if this treatment improves liver function and survival.
This trial tests if infusions of stem cells from donated umbilical cords can help people with a severe type of liver failure caused by hepatitis B. It aims to see if the treatment is safe and can improve liver function.
This trial looks at how well stem cell (MSC) treatment works for people with severe liver failure caused by hepatitis B. It checks what factors affect the success of the treatment.
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