Vitamin B12 with eye injections for blocked retinal vein
Treatments studied
Part of Eyes & vision, Heart & circulation clinical trials.
This trial tests if adding mecobalamin (a form of vitamin B12) to standard anti-VEGF eye injections helps people with vision loss caused by a blocked vein in the retina. You must have swelling in the back of the eye and have had no prior treatments for this condition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 80 years old
- You have a blocked vein in the retina with swelling in the center of the eye, confirmed by an OCT scan
- Your vision is between 20/400 and 20/40 on an eye chart
- You have never had treatment for this condition, including eye injections, laser, or steroid therapy
- You do not have other eye diseases that cause swelling, like diabetic retinopathy or uveitis
- You are not pregnant, breastfeeding, or have uncontrolled health issues like high blood pressure or diabetes
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new medicine called SMO1 for people with vision loss and swelling in the eye caused by a blocked vein in the retina. It involves regular eye injections to see if the medicine can reduce swelling and improve vision.
This trial tests a tiny needle injection into the artery to dissolve a blockage in the eye's main blood supply. It may help restore vision if the blockage happened within the past week.
This Phase 1 trial tests whether BBC1501, an injection given into the eye, is safe for people with wet age-related macular degeneration (nAMD). It mainly looks at side effects and whether the study injections can be given safely in patients who still have active disease despite prior anti-VEGF treatments.
This Phase 3 study compares a new eye injection (RC28-E) with the standard treatment (aflibercept) for diabetic macular edema, which is swelling in the central retina that affects vision. It aims to see whether the new treatment works as well and is safe.
This study looks at how repeated eye injections of a drug called bevacizumab affect chemicals in your blood that relate to heart health and inflammation. Researchers want to understand if these eye injections might impact your cardiovascular risk.
This study compares two injectable medications (faricimab and biosimilar ranibizumab) used to treat diabetic retinopathy, a serious eye condition that can cause vision loss in people with diabetes. The trial will measure how well each medication works and track specific markers in your eye to understand treatment response.
Hear when a new Retinal Vein Occlusion (RVO) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.