Long-acting pain relief injection for total knee replacement
Part of Pain clinical trials.
This trial studies a long-acting pain medicine called dinalbuphine sebacate for people who had a total knee replacement. The medicine is given as an injection before or during surgery to help control pain for up to several days, and the study will see how well it works and how safe it is.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are having or just had a total knee replacement (a surgery to replace your knee joint with an artificial one) because of wear-and-tear arthritis.
- You are between 50 and 90 years old.
- You are in generally good health (no serious medical conditions that would make surgery risky).
- Your knee problem is not from an inflammatory disease, a recent injury, or an infection.
- You have not had any previous surgery on the same knee.
- You are not allergic to nonsteroidal anti-inflammatory drugs (like ibuprofen), opioids (like morphine), sesame oil, or a certain preservative (benzyl benzoate).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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