Clin2
NCT07142863Possibly a fitNot yet recruiting

Envafolimab plus chemo for stage IIb bone cancer before surgery

OsteosarcomaNeoadjuvant TherapyNeoadjuvant ChemotherapyPD-L1 AntibodyEnvafolimab

Part of Cancer clinical trials.

This trial tests whether adding the immunotherapy drug envafolimab to standard chemotherapy before surgery can help treat stage IIb osteosarcoma (a type of bone cancer) that hasn't spread. The goal is to see if this combination makes the tumor shrink more and improves outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
23 people
Ages
12 years to 70 years
Study type
Interventional

Who can take part

  • You are between 12 and 70 years old.
  • You have been diagnosed with stage IIb osteosarcoma that can be removed with surgery and has not spread to other parts of the body.
  • You have not had any previous cancer treatment, including chemotherapy or radiation.
  • You are in good overall health (ECOG score 0 or 1) and your vital organs (bone marrow, liver, kidneys) are working well.
  • You do not have any other active cancers, serious infections, or autoimmune diseases.
  • You are not pregnant or breastfeeding, and you agree to use effective birth control during the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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