Early radiation vs. observation for high-risk bone metastases
Part of Bones, joints & muscles, Cancer, Pain clinical trials.
This trial tests whether giving radiation therapy early to high-risk but pain-free or nearly pain-free bone metastases can prevent future problems, compared to waiting and monitoring them. It is for people whose cancer has spread to multiple bones and who have certain risky features in those spots.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a type of cancer that started in an organ (like lung, breast, or prostate) and has spread to at least 3 places in your body.
- The bone metastasis that would be treated must cause little or no pain (0-2 on a 0-10 pain scale).
- The bone metastasis must be considered 'high risk' based on its size, location (e.g., hip, shoulder, spine), or how much bone it has damaged.
- You must be 18 or older and able to give informed consent.
- If you could become pregnant, you must not be pregnant and must agree to use highly effective birth control.
- You can have no more than 5 high-risk bone spots that are causing little or no pain.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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