Clinical trials
Bone Metastases clinical trials
Below are recruiting bone metastases clinical trials, each written for real people, not researchers. We’re tracking 54 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07202273Recruiting
One-time radiation treatment for painful bone metastases
This trial tests a single session of radiation therapy to relieve pain and improve stability in up to two bone spots where cancer has spread. The goal is to make treatment faster and more convenient for patients.
Salt Lake City, UtahAges 18 years+ - NCT06367491Recruiting
National database of bone metastases
This study is a national database that collects information from people with cancer that has spread to their bones from a solid tumor. By joining, you will help doctors learn more about bone metastases and improve care for future patients.
Imola, BolognaAges 18 years+ - NCT06065449RecruitingPhase 3
Comparing two radiation therapies for painful bone metastases
This trial compares two types of radiation therapy to relieve pain from cancer that has spread to the bones. It aims to see whether a more targeted, high-dose approach (SBRT) works better than standard palliative radiation.
Houston, TexasAges 18 years+ - NCT07391410Recruiting
A registry study for bone metastases
This study is creating a registry to track information about people with bone metastases (cancer that has spread to the bones) who need treatment for symptoms. It may help researchers learn more about these conditions.
Basking Ridge, New JerseyAges 22 years+ - NCT06470503Enrolling by invitation
Exercise after radiation for bone metastases
This study tests whether a supervised exercise program helps people with cancer that spread to their bones feel stronger and move better after radiation treatment. It is designed for people who can walk independently and have stable bones.
Toronto, OntarioAges 18 years+ - NCT07043608RecruitingPhase 2
Zanzalintinib for kidney cancer that spread to bone
This trial tests a new drug called zanzalintinib for people with advanced clear cell kidney cancer that has spread to the bones (at least 3 spots). The study wants to see if this drug can help slow down or shrink the cancer. It's for patients who have already had some prior treatments.
San Francisco, CaliforniaAges 18 years+ - NCT07146074Recruiting
Early radiation vs. observation for high-risk bone metastases
This trial tests whether giving radiation therapy early to high-risk but pain-free or nearly pain-free bone metastases can prevent future problems, compared to waiting and monitoring them. It is for people whose cancer has spread to multiple bones and who have certain risky features in those spots.
Wilrijk, AntwerpAges 18 years+ - NCT05406063Recruiting
Focused radiation for bone metastases causing pain
This trial studies a precise type of radiation given in multiple small sessions to treat bone metastases that are causing pain. It may help shrink or control the spots in the bone while aiming to reduce side effects by targeting the area closely.
Winterthur, Canton of ZurichAges 18 years+ - NCT05419518RecruitingPhase 2
Higher-dose radiation to ease pain from metastatic tumors
This Phase 2 study tests whether a stronger (higher-dose) radiation plan can better reduce pain from tumors that have spread to bone or other areas. It’s meant to help people live more comfortably by targeting painful spots while avoiding certain high-risk situations.
Hamilton, New JerseyAges 18 years+ - NCT06524843Recruiting
Evaluating fracture risk from cancer spread to bone
This study looks at people with cancer that has spread to the bones. It uses your medical imaging and records to understand your risk of bone fracture, without testing any new treatment.
Bologna, Emilia-RomagnaAges 18 years+ - NCT06189079Recruiting
Arterial embolization for painful bone metastases
This study tests a procedure called arterial embolization, which blocks blood flow to bone tumors, to see if it can reduce pain or prevent fractures. It is for people with bone cancer that has spread from another cancer (metastases).
Bologna, Emilia-RomagnaAges 18 years+ - NCT06487013Recruiting
Focused ultrasound for painful bone metastases
This trial tests a focused ultrasound treatment called ArcBlate to relieve pain from bone cancer that has spread. It is for people who have moderate to severe pain despite cancer therapy and have chosen not to have surgery or radiation for that pain.
New Taipei CityAges 18 years+ - NCT06918860Recruiting
Nail vs. replacement for bone metastases in upper thigh
This trial looks back at past patients to compare two types of surgery for broken or weak thigh bones caused by cancer that spread. It helps doctors understand which option—a metal nail or a joint replacement—works better.
Bologna, Emilia-RomagnaAges 18 years+ - NCT06805396RecruitingPhase 2
Adding palliative care support during radiation for bone cancer pain
This study tests whether adding a palliative care team early while you receive radiation for bone metastases can improve your quality of life and reduce symptoms.
AmersfoortAges Any age - NCT06987370Recruiting
Radiation study for bone metastases with soft tissue mass
This trial tests a new way of giving radiation (SFRT and SCART) to bone metastases that have a soft tissue mass. It may be an option if you have limited spread and your organs are working well.
Jinan, ShandongAges 18–75 - NCT04947280RecruitingPhase 1/Phase 2
Radiation split into small doses for breast cancer bone spread
This trial studies a type of focused radiation given in smaller parts to treat bone metastases from breast cancer. It may help shrink tumors and improve control of pain or growth when standard treatments haven’t worked or surgery isn’t possible.
Shanghai, Shanghai MunicipalityAges Any age - NCT02356497Recruiting
Study of treatments for bone metastases using routine data
This study follows adults with cancer that has spread to the bones and who are receiving radiation treatment. It looks at how interventional (procedure-based) treatment decisions affect outcomes by using information collected during routine care.
Utrecht, UtrechtAges 18 years+ - NCT04803773Recruiting
MRI-guided ultrasound to treat painful bone tumors
This feasibility study tests an MRI-guided focused ultrasound treatment for certain painful bone tumors, including bone metastases and osteoid osteoma. The goal is to see if the treatment can be safely delivered to the right spot and help with pain.
StrasbourgAges 18 years+ - NCT07028268RecruitingPhase 2
Testing a new drug for bone metastases from solid tumors
This trial tests a new drug called SHR-2017 for people with solid tumors that have spread to the bones. The study aims to see if the drug can help manage pain and other effects of bone metastases.
Guangzhou, GuangdongAges 18 years+ - NCT07112989Recruiting
Building lab models for sarcoma and cancer spread
This study aims to create new laboratory models to better understand sarcomas and cancers that have spread to the bone or lungs. By using donated tumor tissue and blood, researchers hope to learn how these cancers grow and develop, which could lead to better treatments in the future.
BolognaAges Up to 85 years - NCT07197645RecruitingPhase 1
Samarium for pain from bone cancer
This trial tests a new radioactive drug (samarium) given once to reduce severe bone pain from cancer that has spread to the bones. It is for people whose pain is not controlled by current treatments and who cannot have standard radiation.
Miami, FloridaAges 18 years+ - NCT07429422Recruiting
Precise Radiation for Spine Tumors
This trial is testing a very precise radiation technique called SBRT for tumors that have spread to the spine. It aims to see if this approach can treat the tumor effectively while reducing side effects.
LjubljanaAges 18 years+ - NCT06069570RecruitingPhase 1
Gamma delta T cells and low dose radiation for advanced lung or bone cancer
This trial tests a new type of immune cell called gamma delta T cells combined with low-dose radiation to treat people with advanced lung cancer or solid tumors that have spread to the bone. It is only for patients who have already tried standard treatments and either didn't get better or couldn't tolerate them.
Tucson, ArizonaAges 18 years+ - NCT06480955Recruiting
Freezing bone tumors to cure them: a registry study
This trial is studying the use of a freezing treatment called cryoablation to completely destroy bone tumors that have spread from other cancers. It is for people who have only a few tumors or whose tumors are mostly stable, and who are healthy enough to undergo the procedure.
BordeauxAges 18 years+
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Common questions
- Are there clinical trials for bone metastases?
- Yes. Clin2 currently lists 54 recruiting bone metastases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bone metastases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bone metastases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.