Screening for Alpha-1 Antitrypsin Deficiency in Lung Blockage
Treatments studied
Part of Digestive system, Genetic & congenital, Lungs & breathing clinical trials.
This study screens for a rare genetic condition called Alpha-1 Antitrypsin Deficiency in people with lung blockage. It aims to find out if this deficiency is a hidden cause of your breathing problems, which could lead to better treatment options.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your lung function test shows a specific type of blockage (FEV1/FVC ratio 70% or higher).
- You can speak and understand Turkish.
- You are able to understand and answer questions about your health.
- You do not have certain other conditions like kidney disease, active inflammation, rheumatologic or blood diseases, liver disease, COPD, asthma, bronchiectasis, or a history of cancer.
- You are not pregnant and do not use birth control pills.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how alpha-1 antitrypsin deficiency affects the liver over time. It aims to learn more about the disease and find better ways to monitor and treat it.
This trial tests a new medicine called TSRA-196 for people with Alpha-1 Antitrypsin Deficiency who have the PiZZ genetic type. The study looks at whether TSRA-196 can help with lung or liver problems related to this condition.
This trial tests a new treatment called CTX460, which is a type of gene therapy that may correct the genetic defect causing alpha-1 antitrypsin deficiency (AATD) and help slow or improve emphysema. It's designed for adults with severe AATD and emphysema who have not had a liver or lung transplant.
This study checks whether doing alpha-1 screening (genetic test and a blood level test) can help identify alpha-1 antitrypsin deficiency in people at risk. It may be useful if you have symptoms or a family history, but you haven’t had qualifying testing yet.
This study looks at how lung disease changes a type of blood cell called white blood cells. It may help researchers understand what’s happening in the lungs and how to better monitor or treat lung problems.
This study looks at how alpha-1 antitrypsin deficiency affects the liver in adults. It aims to learn more about the liver problems caused by this condition and may help find better ways to manage them.
Hear when a new Alpha 1-antitrypsin Deficiency (AATD) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.