Study of telisotuzumab adizutecan for EGFR-mutated lung cancer
Treatments studied
Part of Cancer, Lungs & breathing clinical trials.
This trial tests a new drug, telisotuzumab adizutecan (given through a vein), alone or with another targeted therapy, versus standard treatments for people with a specific type of advanced lung cancer that has an EGFR mutation and has gotten worse after previous treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced non-squamous non-small cell lung cancer with an EGFR mutation (exon 19 deletion or L858R).
- You have received one prior targeted therapy (a third-generation EGFR TKI) and your cancer has progressed on or after that treatment.
- You are able to provide a recent or archived tumor sample for testing.
- You have a performance status of 0 or 1 (fully active or able to do light work).
- You have at least one measurable tumor that has not been previously treated with radiation.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This trial tests a new drug combination (telisotuzumab adizutecan plus osimertinib) as a first treatment for adults with a specific type of advanced lung cancer that has an EGFR mutation. The goal is to see if the combination is safe and works better than standard care.
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