Clin2
NCT07158008Possibly a fitRecruiting

Weight loss surgery for people with obesity and heartburn

Gastro Esophageal RefluxSevere ObesityBariatric Surgery

Part of Digestive system, Hormones & metabolism clinical trials.

This study compares two weight-loss surgeries for people who have both obesity and severe heartburn or GERD. One surgery combines part of the stomach removal with an anti-reflux wrap, while the other reroutes the stomach to help with weight loss and reflux.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
560 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have a BMI of 40 or more, or a BMI of 35 or more with weight-related health problems like diabetes or high blood pressure.
  • You have significant heartburn or acid reflux that requires medication (PPIs) or you have been diagnosed with esophagitis (inflammation of the esophagus) grade B or higher.
  • You have not had any prior surgery on your stomach or esophagus for reflux or weight loss.
  • You are not a smoker and have no history of smoking.
  • You are not pregnant or planning to become pregnant during the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06783751Recruiting
New surgical method to reduce acid reflux after weight loss surgery

This trial tests a modified version of sleeve gastrectomy that aims to reduce the risk of acid reflux (GERD) after surgery. It is for people aged 18–65 with a BMI between 35 and 55 who already have some degree of GERD and are planning to have weight loss surgery.

Orange, California
NCT07747779Recruiting
Comparing two weight-loss surgeries for very high body weight

This study compares two types of weight-loss surgery to see how they affect hormones after a meal. It may help you choose a surgery that improves your health and weight loss.

Pathum Wan, Bangkok
NCT06757296Recruiting
Endoscopic revision of sleeve gastrectomy for reflux or poor weight loss

This study tests a new, less invasive way to convert a sleeve gastrectomy into a different type of weight-loss surgery (SASI) in people who have ongoing gastroesophageal reflux or haven't lost enough weight. The goal is to see if this endoscopic procedure can improve reflux and help with weight loss without the need for a traditional surgery.

Singapore
NCT04763993Not yet recruiting
Comparing acid reflux after two weight-loss surgeries

This study compares two common weight-loss surgeries (gastric bypass and sleeve gastrectomy) to see which is better at treating acid reflux in people with obesity. If you have reflux and are considering surgery, this trial will randomly put you in one of the two surgery groups.

NCT05611697Recruiting
Compare two weight-loss surgeries for severe obesity

This trial compares two types of bariatric (weight-loss) surgery to see which helps people with severe obesity lose weight and stay healthy. You might be eligible if you’re between 20 and 60 and are already being referred for bariatric surgery after prior unsuccessful weight-loss attempts.

Tønsberg, Vestfold
NCT03692455Enrolling by invitation
Compare two weight-loss surgeries for reflux over 8 years

This study follows people for up to 8 years to see how two different weight-loss surgeries affect ongoing heartburn and acid reflux. You would join only if you were already enrolled in an earlier related study and can complete required follow-up visits and tests.

Passo Fundo, Rio Grande do Sul

Hear when a new Gastro Esophageal Reflux trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.