New brain stimulation for thinking and balance problems in Cushing syndrome
Part of Brain & nervous system clinical trials.
This trial tests a new, minimally invasive brain stimulation technique for people with Cushing syndrome who have developed a condition called cerebellar cognitive affective syndrome (CCAS). It aims to improve both thinking skills and movement coordination.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with Cushing syndrome (confirmed by specific lab tests).
- An MRI shows shrinkage of the cerebellum (the part of the brain that helps with balance and coordination) beyond normal for your age.
- You have been diagnosed with cerebellar cognitive affective syndrome (CCAS) based on a standard test score of 20 or more.
- You have at least moderate trouble with coordination (score of 10 or more on a scale for ataxia).
- You have noticeable problems with thinking, such as memory or attention (score below 26 on a common screening test or low scores in two or more thinking areas).
- You are willing to receive a new type of brain stimulation through a small procedure and can give your written consent.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a combination of gentle brain stimulation paired with specialized exercises designed to help people with cerebellar conditions—disorders affecting balance, coordination, and movement. The goal is to see if pairing these two approaches together works better than either alone.
This trial tests a noninvasive brain stimulation method (tACS) to see if it can improve thinking, memory, and social abilities in people with cerebellar conditions. It may help if you have a cerebellar malformation or degenerative atrophy and are between 12 and 32 years old.
This study tests a noninvasive electrical stimulation therapy applied to the spine to see if it can improve movement and coordination in people with spinocerebellar ataxia. It may help with walking and balance.
This trial tests whether stimulating a part of the brain called the cerebellum with a device can help improve balance and coordination in people with primary ataxia (a movement disorder you were born with or inherited). It aims to see if this treatment is safe and effective over one year.
This trial tests if a gentle electrical current applied to the scalp can help people with a specific type of multiple system atrophy (the cerebellar variant) improve walking and other symptoms. The goal is to see if this non-invasive treatment is safe and effective.
This trial tests a brain stimulation technique (tACS-iTBS) on the cerebellum to see if it can improve coordination and movement problems caused by ataxia. It might help if you have a stable medication routine and can follow instructions.
Hear when a new Cerebellar Atrophy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.