Clin2
NCT07168668Possibly a fitNot yet recruiting

Combined immunotherapy and targeted liver treatment for unresectable liver cancer

HCCTaceImmunotherapy

Part of Cancer, Immune system & allergy clinical trials.

This trial tests whether adding a liver-directed treatment to standard systemic therapy can improve outcomes for people with liver cancer that cannot be removed. It may help shrink tumors or slow the disease while on current treatment.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
90 people
Ages
20 years and older
Study type
Interventional

Who can take part

  • You have liver cancer that cannot be surgically removed, and you are currently receiving systemic treatment (like pills or infusions).
  • Your largest tumor is no more than 15 cm and the total tumor size is under 20 cm.
  • You are at least 18 years old and able to make your own medical decisions.
  • Your liver function and overall health are within acceptable ranges (based on blood tests).
  • Your daily activities are not significantly limited (ECOG score 0 or 1).
  • You have not had radiation to the liver or previous liver-directed internal radiation therapy.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07128251Not yet recruiting· Phase 2
TACE plus immunotherapy and bevacizumab for liver cancer

This study combines a liver-directed procedure called TACE (which blocks blood flow to the tumor and delivers chemotherapy directly to it) with two immunotherapy drugs and a targeted therapy (bevacizumab). The goal is to see if this combination can shrink liver cancer that cannot be surgically removed, without the cancer having spread elsewhere.

NCT05970666Recruiting· Phase 2
TACE plus immunotherapy and VEGF drug for unresectable liver cancer

This trial tests whether combining TACE (a liver-targeted chemo procedure) with two medicines—an immune “checkpoint” drug and a blood-vessel blocking drug—can control unresectable hepatocellular carcinoma. It’s designed for people who can’t have surgery or curative ablation, and who still have reasonably strong liver and overall health.

Xiamen, Fujian
NCT06911255Recruiting· Phase 1/Phase 2
Testing two immunotherapy drugs with chemoembolization for liver cancer

This trial tests whether adding two immunotherapy drugs (tremelimumab and durvalumab) to a standard liver cancer treatment called TACE can help people with liver cancer that cannot be removed by surgery. TACE uses tiny particles to block the blood supply to the tumor and delivers chemotherapy directly to the liver.

Seoul
NCT06999707Recruiting· Phase 2
Radiation plus immunotherapy for advanced liver cancer

This trial tests a combination of targeted radiation (photon radiotherapy) with two immunotherapy drugs (tremelimumab and durvalumab) for people with intermediate or advanced liver cancer that can't be surgically removed. The goal is to see if this combination can shrink tumors and improve outcomes.

Taoyuan City, Taiwan
NCT03899428Recruiting· Phase 2
Immune therapy versus targeted therapy for advanced liver cancer

This trial compares an immune “checkpoint” medicine to a targeted cancer medicine in people with advanced liver cancer who have hepatitis B in the blood. It aims to lower hepatitis B surface antigen (HBsAg) levels and see which approach works better and is safest.

Hong Kong, Hong Kong SAR
NCT07100405Recruiting
TACE plus Immunotherapy for Advanced Liver Cancer

This trial tests a combination of two treatments for advanced liver cancer: TACE (a procedure that blocks the blood supply to the tumor) and an anti-PD-1 antibody (a type of immunotherapy that helps your immune system fight cancer). The goal is to see if this combination works better than either treatment alone and to understand how it affects the immune system around the tumor.

Shanghai, Shanghai Municipality

Hear when a new TACE trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.