Screening for cardiac amyloidosis in aortic stenosis patients having TAVR
Part of Heart & circulation clinical trials.
This study looks at whether people having TAVR for aortic stenosis also have a condition called cardiac amyloidosis (abnormal protein buildup in the heart). If you're eligible, the study may help doctors detect this condition and better manage your care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 65 and 85 years old.
- You have moderate to severe aortic stenosis (a common heart valve disease) and are in the hospital to get a TAVR (a procedure to replace that valve).
- Your aortic stenosis is not caused by a birth defect or an autoimmune disease like rheumatic fever.
- You do not have severe kidney problems (like needing dialysis) or an unresolved acute kidney injury.
- You are expected to live more than 6 months (no terminal illness).
- You are able to come to the scheduled follow-up visits.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how calcium buildup in the aortic valve affects long-term results after a TAVR procedure (a minimally invasive heart valve replacement). It may help doctors understand which patients do better over time.
This study tests whether continuing a beta-blocker (a heart medication) improves outcomes for people having a planned TAVR (a minimally invasive heart-valve replacement). It may help doctors decide whether to keep or stop this medicine after the procedure.
This study looks at how often cardiac amyloidosis occurs in people with severe aortic valve stenosis. It uses different heart scans to find out more. If you have both conditions, this research may help doctors understand your situation better.
This trial studies whether a new through-the-blood-vessel heart valve (TAVR) is safe and works well for people with severe aortic stenosis who are too risky for traditional surgery. If you qualify, you would be closely followed to check your symptoms and valve function over time.
This study tests a new replacement valve for the aortic heart valve, delivered through a catheter (a thin tube) — a procedure called TAVR. It is for people who have severe aortic stenosis and are not good candidates for open-heart surgery.
This study follows people with aortic stenosis who are getting a TAVI valve replacement. It uses imaging tests (MRI and CT) to learn more about the condition and improve future care.
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