Ventilator settings to protect lungs during high-risk surgery
Part of Lungs & breathing clinical trials.
This study compares two ways of setting the ventilator during surgery to reduce lung complications. Researchers will test whether using a lower 'driving pressure' (a setting on the breathing machine) helps protect the lungs better than usual care. It is for adults having high-risk surgeries under general anesthesia with a breathing tube.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are scheduled for surgery under general anesthesia with a breathing tube.
- Your preoperative risk score (ARISCAT) for lung problems after surgery is 26 or higher.
- You are not pregnant or a new mother (within the first few weeks after childbirth).
- You do not have severe heart failure, severe irregular heartbeat, or severe lung disease (like emphysema).
- You can safely receive muscle relaxant medicines and have your breathing temporarily stopped during the surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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