Lenalidomide and dexamethasone for Rosai-Dorfman disease
Treatments studied
Part of Blood & lymphatic clinical trials.
This trial tests a combination of two drugs, lenalidomide and dexamethasone (called the RD regimen), for people with Rosai-Dorfman disease, a rare disorder that causes immune cells to build up in the body. Researchers want to see if this treatment is safe and effective for patients who are newly diagnosed or whose disease has come back or not improved with other treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 to 80 years old.
- You must have a confirmed diagnosis of Rosai-Dorfman disease.
- You can be new to treatment or have tried other therapies that didn't work.
- You should be able to do daily activities with little or no help (ECOG score 0-2).
- You must not have serious heart, kidney, liver, or blood problems.
- You must be willing to use effective birth control if applicable, and not be pregnant or nursing.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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