Clin2
NCT07189936Possibly a fitRecruiting

Testing 2-HOBA for Immune Issues in Long COVID with POTS

Post-Acute COVID-19 SyndromePostural Tachycardia Syndrome (POTS)SARS CoV 2 InfectionLong COVID19

Part of Brain & nervous system, Infections, Lungs & breathing clinical trials.

This trial tests if a medication called 2-HOBA can help with ongoing immune system issues in people with Long COVID who also have POTS. It aims to reduce fatigue and other symptoms by calming overactive immune responses.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
50 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have been diagnosed with Long COVID (symptoms lasting over 3 months after COVID-19)
  • You have been diagnosed with POTS (rapid heartbeat when standing up)
  • Your COVID-19 infection happened at least 3 months ago and was confirmed by a test or doctor's note
  • You are not pregnant or breastfeeding, and have no active heart disease, diabetes, or autoimmune conditions
  • You have normal liver and kidney function, and are not severely anemic

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05375968Recruiting· Phase 2
Test blood-flow changes in POTS after meals

This Phase 2 study looks at how blood pools in the belly veins when you stand or eat, in people with POTS (postural tachycardia syndrome). The goal is to understand what’s driving symptoms like feeling nearly faint and whether this helps guide better care.

Nashville, Tennessee
NCT07074158Enrolling by invitation
Looking for long COVID clues in blood

This study compares the blood of people with ongoing long COVID symptoms to healthy people, to look for differences in immune signals and gut bacteria. It could help find better ways to diagnose or treat long COVID.

Palo Alto, California
NCT06631287Recruiting· Phase 3
Testing baricitinib for persistent long COVID symptoms

This trial tests whether the anti-inflammatory drug baricitinib can improve persistent long COVID symptoms like brain fog, fatigue, and shortness of breath. You may qualify if you had COVID-19 at least 6 months ago and still have bothersome symptoms that affect your daily life.

Tucson, Arizona
NCT05914649Recruiting
Testing long COVID and POTS brain fog symptoms

This study tests how different long-COVID and POTS-related symptoms—especially “brain fog”—show up and improve. It may help researchers better measure symptoms so future treatments can be targeted more effectively.

Calgary, Alberta
NCT06883513Recruiting
Osteopathic therapy for long COVID symptoms

This trial tests if gentle hands-on treatment (osteopathic manipulative therapy) can help relieve long-lasting COVID symptoms like fatigue, brain fog, and body pain.

Louisville, Kentucky
NCT05894616Recruiting
Home monitoring study for lasting breathing symptoms after COVID

This study looks at people with lingering post-COVID symptoms, especially breathing and lung-related findings, using home monitoring and medical tests. It may help researchers understand what’s driving ongoing symptoms and identify patterns that could guide better care.

Stockholm, Sverige

Hear when a new Post-Acute COVID-19 Syndrome trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.