Clinical trials
Post-Acute COVID-19 Syndrome clinical trials
Below are recruiting post-acute covid-19 syndrome clinical trials, each written for real people, not researchers. We’re tracking 26 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07781501Recruiting
Study of long-term effects of covid-19
This study looks at the long-term effects of COVID-19, sometimes called Long COVID. By studying saliva and health info, researchers hope to understand why some people have lasting symptoms.
Chapel Hill, North CarolinaAges 18–75 - NCT06248151Recruiting
Exercise and heart health after COVID-19
This study looks at how a single exercise session affects the heart and blood vessels in people with lasting COVID-19 symptoms. It may help understand if exercise is safe and helpful for recovery.
São PauloAges 18 years+ - NCT04890483Recruiting
Brain stimulation to ease pain and fatigue after COVID
This study tests whether a noninvasive brain stimulation treatment can reduce fatigue and body pains after COVID in people with autoimmune diseases. It may help symptoms by changing brain activity without surgery.
São PauloAges 18–80 - NCT07400848Recruiting
Symptoms and recovery after COVID-19 vaccine
This study looks at people who developed new, long-lasting symptoms after a COVID-19 vaccine. It aims to understand their symptoms, do lab tests, and see how they recover over time.
BernAges 18 years+ - NCT06776263Recruiting
Breathing problems after COVID-19 study
This study looks at people who have ongoing breathing issues after a COVID-19 infection. It tests a simple questionnaire to see if you have dysfunctional breathing (abnormal breathing patterns) and may help guide treatment.
Stockholm, SolnaAges 18 years+ - NCT05822193Recruiting
Study of long COVID in Brazil
This study looks at how often “post-COVID-19 condition” (long COVID) happens, what factors are linked to it, and how much it affects people’s daily lives. It may help researchers better understand long COVID and who is most impacted.
Cachoeirinha, Rio Grande do SulAges 18 years+ - NCT07356570Recruiting
Post-COVID care tracking study for long-term symptoms
This study follows people with lasting or complex COVID-19 symptoms who are already in a specialized care program. It aims to better understand and improve recovery after COVID.
Pierre-BéniteAges 18 years+ - NCT06883513Recruiting
Osteopathic therapy for long COVID symptoms
This trial tests if gentle hands-on treatment (osteopathic manipulative therapy) can help relieve long-lasting COVID symptoms like fatigue, brain fog, and body pain.
Louisville, KentuckyAges 18 years+ - NCT06590324RecruitingPhase 2/Phase 3
Study of Apabetalone for long COVID
This trial tests an experimental drug called Apabetalone for people with long COVID. You may be eligible if you have type 2 diabetes, take or are willing to take dapagliflozin, and have had long COVID symptoms for at least 2 months after your COVID infection.
AmmanAges 18 years+ - NCT07197138Recruiting
TMS for depression with long COVID
This trial tests whether accelerated TMS (a brain stimulation treatment) can help people with depression who also have long COVID. It may be an option if your depression hasn't improved enough with medication alone.
Munich, BavariaAges 18–65 - NCT07189936RecruitingPhase 2
Testing 2-HOBA for Immune Issues in Long COVID with POTS
This trial tests if a medication called 2-HOBA can help with ongoing immune system issues in people with Long COVID who also have POTS. It aims to reduce fatigue and other symptoms by calming overactive immune responses.
Nashville, TennesseeAges 18 years+ - NCT07140094Recruiting
Long COVID Relief Through Learning Mindfulness
This study tests whether a mindfulness program can help ease long COVID symptoms. You will learn simple mindfulness techniques and see if they improve your daily life.
New York, New YorkAges 18 years+ - NCT07076862RecruitingEarly Phase 1
PET scan study for long COVID symptoms
This study uses a special PET scan to look at inflammation in the body of people with long COVID (symptoms lasting 3+ months after infection). The goal is to understand why symptoms persist and find better ways to help.
Sacramento, CaliforniaAges 18 years+ - NCT07074158Enrolling by invitation
Looking for long COVID clues in blood
This study compares the blood of people with ongoing long COVID symptoms to healthy people, to look for differences in immune signals and gut bacteria. It could help find better ways to diagnose or treat long COVID.
Palo Alto, CaliforniaAges 18 years+ - NCT06960928RecruitingPhase 3
Low dose sirolimus for long COVID
This trial tests if a low dose of sirolimus, a medicine that calms the immune system, can help people with long COVID. If you have had long COVID symptoms for at least 6 months, like severe fatigue, brain fog, or chest pain, you may be able to join.
New York, New YorkAges 18 years+ - NCT06850350Recruiting
Long COVID and Thinking & Walking
This study looks at how Long COVID affects thinking and movement skills. If you had COVID-19 more than 3 months ago and could walk before you got sick, you may be able to help researchers understand these lasting symptoms.
Chicago, IllinoisAges 18 years+ - NCT06168006Recruiting
Exercise app for heart health after COVID
This study tests whether a smartphone exercise app can improve heart health and physical function in people who still have symptoms like fatigue or shortness of breath after COVID-19. If you qualify, you'll use the app to follow a home exercise program.
São Paulo, São PauloAges 18 years+ - NCT06086379Enrolling by invitation
Cognitive rehab therapy for COVID-related thinking problems in Veterans
This study tests a cognitive rehabilitation therapy designed to help Veterans who have memory and thinking problems after COVID-19. It aims to improve daily mental function and quality of life.
San Diego, CaliforniaAges 18 years+ - NCT06095297Recruiting
Cognitive rehab for brain fog from long COVID
This study tests a computer-based cognitive training program combined with a gentle nerve stimulation device to see if it can improve brain fog and daily functioning in people with long COVID. If you're struggling with thinking, memory, or concentration after COVID, this might help.
Birmingham, AlabamaAges 18 years+ - NCT05977179Recruiting
Diet program for long-COVID fatigue and poor diet quality
This study tests whether improving diet quality can reduce fatigue and symptoms in people with long-COVID (post-acute COVID-19 syndrome). It may help if your diet quality is currently low and your fatigue is moderate to severe.
Baltimore, MarylandAges 50–94 - NCT05926505RecruitingPhase 2/Phase 3
Anakinra for lingering symptoms after COVID-19
This Phase 2/3 trial studies whether anakinra can improve ongoing (post-acute) COVID-19 symptoms lasting for more than two months. It mainly looks for better safety and symptom improvement in people with specific inflammation and lung-related findings.
JenaAges 18 years+ - NCT05787379Recruiting
Care program for Veterans with long-lasting COVID symptoms
This trial tests a care approach for Veterans who have long-COVID—aiming to improve symptoms and follow-up care through participating VA clinicians. You may be included if you are a Veteran with long-COVID and can be seen by a participating clinician soon, unless you had severe COVID requiring ICU care.
East Orange, New JerseyAges Any age - NCT04806620Recruiting
Online app study for brain inflammation lifestyle data
This study uses a digital platform (app/website) to collect lifestyle and symptom information to better understand brain inflammation. You may qualify if you have certain conditions like Long COVID, migraines, autoimmune disease, inflammatory gut issues, mood disorders, or if you are a healthy comparison person.
Delafield, WisconsinAges 2 years+ - NCT05350774Enrolling by invitationPhase 2
IV immunotherapy for lingering neurologic effects after COVID-19
This Phase 2 trial tests whether intravenous immunotherapy (IVIG) can improve ongoing neurologic symptoms after a mild-to-moderate COVID-19 illness. It targets people with persistent symptoms such as brain fog, fatigue, trouble thinking, dizziness when standing, and balance or other neurologic problems.
Bethesda, MarylandAges 18–100
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Post-Acute COVID-19 Syndrome trials by city
Studies with a site in or near these metro areas.
Common questions
- Are there clinical trials for post-acute covid-19 syndrome?
- Yes. Clin2 currently lists 26 recruiting post-acute covid-19 syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a post-acute covid-19 syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a post-acute covid-19 syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.