Clin2
NCT07190625Possibly a fitRecruiting

Fentanyl spray versus injection for pain in preterm babies

Procedural Pain

Treatments studied

Part of Pain clinical trials.

This trial compares giving fentanyl as a nasal spray versus an injection to help preterm babies during painful procedures like placing a central line, inserting a breathing tube, or a spinal tap. The goal is to see which method works better and is safer.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
75 people
Ages
Up to 4 weeks
Study type
Interventional

Who can take part

  • Your baby was born early, between 28 and 36 weeks of pregnancy.
  • Your baby needs a painful procedure like a central line, breathing tube, or spinal tap.
  • Your baby has not had a bad reaction to fentanyl before and does not have liver failure.
  • Your baby does not have any blockage or sores in the nose that would prevent using nasal spray.
  • Your baby has not had surgery recently and is not already on fentanyl or midazolam infusions.
  • Your baby does not have a serious brain condition like severe bleeding or injury.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07422558Not yet recruiting
Comparing two medicines to prevent pain from propofol injection

This study tests whether nalbuphine or lidocaine works better at reducing the pain felt when propofol is injected during general anesthesia. If you are having planned surgery with propofol, you may be able to join.

NCT06882655Not yet recruiting
Pain block and fentanyl for children's heart surgery

This trial tests a pain-relief method combining a nerve block in the chest with fentanyl (a strong pain medicine) given through the spine for children aged 6 months to 6 years having heart surgery. The goal is to see if this approach works better and reduces the need for other strong pain medicines after surgery.

Alexandria, Alexandria Governorate
NCT07332130Not yet recruiting· Phase 1
Spinal pain relief during labor

This study tests spinal injections to manage labor pain in pregnant women. It aims to see if this method provides safe and effective pain relief during childbirth.

Minya
NCT07112430Not yet recruiting· Phase 1/Phase 2
Nasal Fentanyl for Pain During Preterm Eye Exams

This study tests whether fentanyl (a pain medicine given as a nasal spray) can help preterm babies feel less pain during a routine eye exam for retinopathy of prematurity. It is designed for babies who are stable and need this exam as part of their NICU care.

Halifax, Nova Scotia
NCT06832046Recruiting
Intranasal fentanyl for pain in pediatric emergencies

This study looks back at children who already received fentanyl nasal spray for pain in the emergency department. It aims to see how well this method worked for treating sudden pain in children.

Strasbourg
NCT06968546Not yet recruiting· Phase 2
Nasal spray for severe pain after a child's injury

This trial tests two different nasal sprays (sufentanil vs ketamine) to quickly relieve severe pain from a recent arm or leg injury in children. It aims to find which works better and is safer.

Nice, France

Hear when a new Procedural Pain trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.