Clinical trials
Procedural Pain clinical trials
Below are recruiting procedural pain clinical trials, each written for real people, not researchers. We’re tracking 88 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06520150Recruiting
Comparing two numbing methods for S-ICD heart device placement
This study compares two ways of numbing the chest area (regional anesthesia) for people getting an S-ICD heart device. The goal is to find which method works better and is safer for patients who are at higher risk for general anesthesia.
Wroclaw, Lower Silesian VoivodeshipAges 18–90 - NCT05895383RecruitingPhase 4
Nitrous oxide breathing during vasectomy: a feasibility study
This study looks at whether self-adjusting nitrous oxide (a calming gas) with oxygen can be safely and comfortably used during a vasectomy, and how people experience it. You may be offered the gas to see how it fits into care during the procedure.
Boston, MassachusettsAges 21–85 - NCT07746973Enrolling by invitation
Magic show to reduce pain and fear during needle procedures
This study tests whether watching a magic show called 'Kuco' during a needle procedure (like getting blood drawn or an IV) helps children aged 5 to 8 feel less pain and fear. If your child needs a needle and can watch the show, they might be eligible to join.
Bingoel, BingölAges 5–8 - NCT07650591Recruiting
Tapping and vibration to ease needle pain in children
This study tests whether rhythmic tapping and gentle vibration near the skin can help children ages 6–12 feel less pain and fear during blood draws. Researchers want to see if these simple techniques can make the procedure more comfortable.
Antalya, KepezAges 6–12 - NCT06471075Recruiting
Mindfulness for Pain Before Orthopedic Procedure
This study tests whether a short mindfulness (calm focus) exercise before an in-clinic orthopedic procedure can help reduce pain. If you are getting kyphoplasty or radiofrequency ablation at Tallahassee Orthopedic Center, this brief program might make your experience more comfortable.
Tallahassee, FloridaAges 18 years+ - NCT05961800Recruiting
Study ways to evaluate lumbar back pain blocks
This study looks at how well different methods can evaluate a common procedure used for chronic low back pain (lumbar medial branch blocks). If you have long-lasting, everyday back pain and are having this procedure, you may help researchers compare evaluation approaches.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07094451Recruiting
Virtual reality for pain during needle procedures
This study tests whether using a virtual reality headset can help reduce pain during ultrasound-guided needle procedures in pregnancy. It may offer a drug-free way to feel more comfortable during the procedure.
New York, New YorkAges 18 years+ - NCT06913270Recruiting
Virtual reality for pain during burn dressing changes
This study tests whether using virtual reality (VR) during dressing changes can help reduce pain and anxiety for adults with burn injuries. If you have moderate to severe pain during dressing changes, this approach might offer extra comfort without extra medication.
CairoAges 18–65 - NCT06944314Enrolling by invitation
Doctors' views on pain during flexible cystoscopy with local anesthetic
This trial asks doctors to rate how much pain they think male patients feel during a minimally invasive bladder exam. It aims to see if doctors' estimates of pain are accurate.
Istanbul, IstanbulAges 18 years+ - NCT05275881Recruiting
Virtual reality during procedures for young blood or cancer patients
This trial tests whether using virtual reality (VR) during certain procedures can make them easier for children, teens, and young adults with blood or cancer-related conditions. Participants must be able to safely use a VR headset and be willing to take part.
PoitiersAges 7–24 - NCT06284473RecruitingPhase 4
Ketamine with numbing medicine for minor emergency procedures
This study tests whether adding ketamine to the usual numbing medicine makes minor procedures in the emergency department less painful. You may be a good fit if you are having a small procedure like stitches or abscess drainage.
Maywood, IllinoisAges 7–70 - NCT06984939Recruiting
Handheld distraction tool for kids during needle procedures
This study tests a small handheld tool that may help distract children and teenagers during painful procedures like getting an IV, a blood draw, a dental needle, or if you have just been diagnosed with type 1 diabetes and need frequent blood checks and insulin shots. The tool is meant to make the experience less stressful.
Bergen, VestlandAges 8–15 - NCT06799052Recruiting
Cervical preparation for same-day abortion procedure
This study compares two methods of preparing the cervix (the opening to the uterus) on the same day as a dilation and evacuation (D&E) procedure for abortion at 16 to 18 weeks of pregnancy. The goal is to see which preparation approach works best and is safest.
Boston, MassachusettsAges 16 years+ - NCT07427862Recruiting
Virtual reality for kids having interventional radiology
This study tests if using virtual reality (VR) during interventional radiology procedures can help children feel more comfortable and less anxious. It is looking for children ages 8 and older who are in the normal range of development.
Los Angeles, CaliforniaAges 8 years+ - NCT05673551Enrolling by invitation
VR during at-home burn dressing changes for kids
This trial tests whether virtual reality (VR) can help children feel better during daily burn dressing changes at home. It will study comfort and pain around the first time you do dressings after leaving the hospital.
Columbus, OhioAges 6–17 - NCT05458037Recruiting
Testing fast versus slow numbing during IUD or biopsy
This study compares two ways of applying a numbing tool (“tenaculum”) during an IUD insertion or an endometrial biopsy to see which one causes less pain. If you’re scheduled for one of these procedures, it may help improve how discomfort is managed.
Providence, Rhode IslandAges 18 years+ - NCT06692400Recruiting
Suctioning, pain, and blood markers in intubated patients
This study looks at how routine suctioning of the breathing tube affects pain levels and certain substances in the blood in adults who are on a breathing machine for serious infections like flu, pneumonia, COVID, or sepsis. It may help doctors better understand and manage your comfort during this procedure.
Loma Linda, CaliforniaAges 18 years+ - NCT06723158Recruiting
Virtual reality glasses for oral surgery with sedation
This trial tests if wearing virtual reality (VR) glasses during oral surgery helps patients relax while under IV sedation. It may be a good option if you need sedation for a tooth extraction or other mouth procedure.
Boston, MassachusettsAges 16–65 - NCT07669961Recruiting
Distraction cards vs toy squeezing for kids getting shots
This trial compares using distraction cards or a squeezable toy to help children aged 4–7 feel less pain and fear during a routine vaccination shot.
Mersin, ProvinceAges 4–7 - NCT07484815Recruiting
Virtual reality for pain during egg freezing
This study tests whether using a virtual reality (VR) headset during egg freezing can help reduce pain. If you are having your eggs retrieved to preserve your fertility, you may be able to take part and wear a VR device to see if it makes the procedure more comfortable.
JerusalemAges 18–45 - NCT07761689Recruiting
Kangaroo care for pain relief during newborn jaundice light therapy
This study tests whether holding your baby skin-to-skin (kangaroo care) during light therapy for jaundice can help reduce their pain and discomfort. It aims to see if this simple comfort measure is beneficial.
IstanbulAges 2 days–1 week - NCT06795126Enrolling by invitation
Virtual reality for pain and anxiety in kids getting IVs
This study tests if a virtual reality game called Little NIRVANA can help reduce pain and anxiety in children getting an IV. It's for kids ages 2 to 8 in the emergency department.
Columbus, OhioAges 2–8 - NCT07763132Recruiting
Virtual reality for needle pain in children
This study compares using virtual reality goggles, a numbing cream, or standard care to reduce pain and anxiety during blood draws in children aged 3 to 15. It aims to find which method works best to make the experience more comfortable.
Ústí nad Labem, Ústí nad Labem RegionAges 3–15 - NCT07747649Recruiting
Multisensory stimulation for pain from newborn heel pricks
This study tests whether combining gentle touches, sounds, and other sensory input can reduce pain when newborns get a routine heel prick for blood tests. If you have a healthy newborn staying with you in the hospital's newborn care unit, this might make those pricks less uncomfortable.
Ankara, BeşevlerAges 1 day–4 weeks
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Procedural Pain trials by city
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Procedural Pain trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for procedural pain?
- Yes. Clin2 currently lists 88 recruiting procedural pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a procedural pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a procedural pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.