Tirzepatide for treating high pressure in the brain
Treatments studied
Part of Brain & nervous system, Pain clinical trials.
This trial tests if tirzepatide can help lower the pressure inside your skull caused by a condition called Idiopathic Intracranial Hypertension. It's designed for people with a BMI of 30 or higher who have swelling of the optic nerve.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have signs of high pressure in the brain such as headaches, ringing in the ears, blurry vision, or swelling of the optic nerve.
- Your body mass index (BMI) is 30 or higher.
- You are between 18 and 60 years old.
- You have some swelling of the optic nerve in one or both eyes.
- You are willing to use reliable birth control if you could become pregnant.
- You have not had weight loss surgery, certain thyroid or pancreas problems, or a history of gallbladder disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This trial tests whether placing a small tube (stent) in a narrowed brain vein can help people with newly diagnosed intracranial hypertension (high pressure in the head) that causes vision problems. It is for those who have not yet taken standard medication and have specific vein narrowing seen on MRI.
This trial tests whether placing a stent (a small tube) in a narrowed brain vein can help reduce pressure in the head in people with Intracranial Hypertension who have been on acetazolamide for over a year. It may be an option if you still have high pressure despite medication.
This trial tests if a small tube called a stent can be placed in a vein in your brain to relieve high pressure. It may help people with headaches, vision changes, or other symptoms from this condition.
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This trial tests if the weight loss medication tirzepatide can help young adults (18–40) with obesity and high blood pressure lower their blood pressure. It compares standard care to weight loss with tirzepatide.
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