Cenerimod for Active Lupus Nephritis
Part of Immune system & allergy, Kidney & urinary, Skin, Women’s health & pregnancy clinical trials.
This trial tests if an investigational drug called cenerimod can safely and effectively treat active lupus nephritis when added to your regular lupus medications. It's for people with recent kidney biopsy showing active lupus kidney disease and high protein in urine.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a lupus-related kidney problem called lupus nephritis, confirmed by a recent kidney biopsy showing class III, IV, or pure class V.
- You have high protein levels in your urine, a sign of active kidney disease.
- Your kidney function is at least 15% of normal (eGFR of 15 or higher), and if it's between 15 and 30, your kidney biopsy must show limited scarring.
- You agree to take standard treatments for lupus nephritis: mycophenolate (CellCept or Myfortic) and high-dose steroids (pills and possibly IV).
- You cannot have severe lupus affecting the brain, other serious kidney diseases, certain heart rhythm problems, or active infections like tuberculosis or hepatitis.
- If you can get pregnant, you must use very effective birth control and take pregnancy tests during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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