Studying cholesterol's role in memory and thinking decline
Part of Brain & nervous system, Mental health clinical trials.
This study looks at how cholesterol and related substances in the body may be linked to the development and progression of certain dementias. It aims to find better ways to understand and track these diseases.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 40 and 85 years old
- You have a diagnosis of Alzheimer's disease, frontotemporal dementia, progressive supranuclear palsy, or corticobasal degeneration based on current medical criteria
- Your score on a common dementia test (MMSE) is above 10
- You do not have other major brain or mental health conditions
- You do not have severe long-term metabolic diseases (like severe diabetes or thyroid disease)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether lowering blood pressure and cholesterol can protect thinking and memory in people with a genetic risk for Alzheimer’s (the APOE e4 gene). If you are 50–75, have moderately high cholesterol and blood pressure, and do not have dementia, you may be able to join.
This study looks at how well people with Alzheimer’s disease (AD) or mild cognitive impairment (MCI) perform on standardized memory/brain tests. It may help researchers understand changes over time, and whether certain types of brain signals or test results track with the condition.
This study tests whether combining a digital brain-training program with strong cholesterol-lowering medication can help improve thinking and memory in people with narrowing of arteries inside the brain. The goal is to reduce stroke risk and cognitive decline.
This study looks for ways to lower the risk of developing dementia and improve thinking skills in people over 60. You may be eligible if you do not have dementia but have early warning signs of memory or thinking changes.
This study looks at what factors might increase the risk of memory and thinking problems in people with coronary heart disease. It includes testing your memory and metabolism during a hospital stay.
This study looks at memory and thinking changes using questionnaires, memory testing, and brain scans. It may help researchers better understand neurodegeneration and dementia and how these problems show up over time.
Hear when a new Dementias trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.