Probiotics for Digestion During Weight-Loss Treatment
Part of Digestive system, Hormones & metabolism clinical trials.
This study tests whether taking a probiotic (a type of 'good' bacteria) can improve digestion and gut health in people who are starting a GLP-1 RA medicine for weight loss. You would take the probiotic daily and answer questions about your digestive symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old and planning to start a weight-loss medicine called a GLP-1 RA (like semaglutide or tirzepatide).
- Your body mass index (BMI) is 30 or higher, or 27 or higher with a weight-related health problem (e.g., high blood pressure, sleep apnea).
- You do not have diabetes, liver cirrhosis, short bowel syndrome, inflammatory bowel disease (like Crohn's or ulcerative colitis), or a severely weakened immune system.
- You have not taken certain medicines in the last 30 days (including other GLP-1 RA, weight-loss drugs, steroids, antibiotics, probiotics, or prebiotics).
- You have not had weight-loss surgery in the past year, and you are not scheduled for it during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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