Comparing two treatments for thymoma with myasthenia gravis
Part of Brain & nervous system, Immune system & allergy clinical trials.
This trial tests whether a newer drug combination (EFG) works better than standard immunoglobulin (IVIG) for people who have both thymoma and myasthenia gravis and need surgery to remove the thymoma. The goal is to improve symptoms before and after the operation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old
- You have generalized myasthenia gravis (muscle weakness affecting more than just the eyes)
- Your myasthenia gravis symptoms score (MG-ADL) is 6 or higher on a 0–24 scale
- You have a type of thymoma (a tumor in the chest) shown on a CT or MRI scan
- A team of doctors has confirmed you need surgery to remove the thymoma
- You are in good overall health (American Society of Anesthesiologists grade 1 or 2) and have no major heart, lung, liver, kidney, or bleeding problems
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests an experimental drug called efgartigimod (given through an IV) for people with a rare type of myasthenia gravis that doesn't show up on standard antibody tests. It aims to see if the drug can improve muscle weakness and daily function.
This trial tests giving a medication called efgartigimod before and after surgery for people who have both thymoma (a thymus tumor) and myasthenia gravis. The goal is to see if it helps improve muscle strength and recovery after tumor removal.
This trial tests whether a follow-up treatment with ublituximab (given as an infusion) can help myasthenia gravis patients who first received efgartigimod. The goal is to see if it provides lasting control of MG symptoms.
This study tests a medication called efgartigimod for people with myasthenia gravis who need regular IVIG treatments. The goal is to see if efgartigimod can help reduce the need for IVIG.
This trial tests whether taking two drugs one after the other—efgartigimod followed by telitacicept—is safe and effective for people with generalized myasthenia gravis. It may offer a new treatment option if standard therapy isn't enough.
This trial tests a drug called efgartigimod for people with myasthenia gravis who are experiencing a sudden, severe worsening of symptoms (crisis). The drug may help reduce the need for a breathing tube or speed up recovery.
Hear when a new Myasthenia Gravis Associated With Thymoma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.