Periodontal treatment for Alzheimer's disease

This trial studies whether treating periodontal (gum) disease can help people who have probable Alzheimer’s disease. You may take a study treatment and have regular checks by a caregiver and study team.

This study looks at the bacteria in the mouth (periodontal microbiota) to see whether they differ between seniors with Alzheimer’s disease and seniors without it. You may be asked for a sample from your gums/teeth and background health information.

This trial tests five different non-surgical gum treatments to see how they affect overall health. It may be a good fit for people with advanced gum disease who do not smoke heavily or take certain medications.

This trial tests whether a gel made from hyaluronic acid helps rebuild bone and gum tissue around teeth as well as a standard treatment (enamel matrix derivative). It's for people with advanced gum disease who have completed initial cleaning and still have deep pockets that need repair.

This study looks at how gum disease treatment affects your bite and chewing ability. If you have advanced gum disease, this trial may help show whether your chewing improves with treatment.

This trial tests whether taking probiotics (beneficial bacteria) alongside standard gum disease treatment can help reduce deep pockets in your gums and improve healing. You'd be asked to take probiotics as an add-on to the care you're already receiving.