Clin2
NCT07238465Likely a fitRecruiting

Exploring nervous system function in Down syndrome

Down SyndromeAutonomic Dysfunction

Treatments studied

Part of Brain & nervous system, Genetic & congenital clinical trials.

This trial studies how the nervous system works in people with Down syndrome. It may help understand differences in body functions and improve future care.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
200 people
Ages
18 years to 50 years
Study type
Interventional

Who can take part

  • You are between 18 and 50 years old and generally healthy.
  • You have Down syndrome and can agree to take part.
  • You have a study partner (like a family member or friend) who can come with you to visits.
  • You have no serious heart, lung, or metabolic conditions in the last 6 months.
  • Your body mass index (BMI) is under 45.
  • You are not pregnant or past menopause.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05985486Recruiting
Lifestyle change for brain health in Down syndrome

This study looks at how a healthy lifestyle program can improve brain health in adults with Down syndrome who are overweight or obese. You will attend a medical center three times over a year for tests, and you'll need a caregiver to support you.

Kansas City, Kansas
NCT06943170Recruiting
Aerobic exercise with or without a low calorie diet for teens with Down syndrome

This trial studies how aerobic exercise, alone or combined with a low calorie diet, affects body fat and weight in children with Down syndrome who are overweight or obese. The goal is to find a safe, effective way to help manage weight.

Lahore, Punjab Province
NCT05196984Recruiting
Gamma brain stimulation study for adults with Down syndrome

This trial tests a brain stimulation approach aimed at affecting brain activity in people with Down syndrome. It may help researchers understand whether this kind of stimulation can improve certain brain or thinking-related outcomes.

Cambridge, Massachusetts
NCT04390646Recruiting· Phase 2/Phase 3
Hormone treatment to study thinking in Down syndrome

This trial studies whether a GnRH hormone treatment can improve thinking and memory in people with Down syndrome. It also checks safety and whether the treatment affects brain-related changes seen on MRI.

Lausanne, Canton of Vaud
NCT05231798Recruiting· Phase 2
PET and brain scans in adults with Down syndrome

This study looks at how well a brain chemical system works in adults with Down syndrome as they age, including how it relates to Alzheimer’s-type brain changes and thinking skills. It uses brain scans and memory/thinking tests to see whether these measures can help track risk or changes over time.

Nashville, Tennessee
NCT07625579Recruiting
Collaboration for Down Syndrome Progress Research Study

This research study aims to better understand Down syndrome by collecting health information, family history, and sometimes brain imaging or sleep data from children and adults with Down syndrome and their families. The goal is to advance knowledge that could improve health and development for people with Down syndrome.

Orange, California

Hear when a new Down Syndrome trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.