Comparing pain-relief medicines after knee surgery
Part of Bones, joints & muscles, Pain clinical trials.
This study compares two pain-relief medicines added to the standard numbing drug for a nerve block around the knee. The goal is to find which one works better to reduce pain after knee surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled for knee surgery.
- The surgery will use spinal anesthesia (numbing from the waist down).
- You are generally in good health (no serious heart, lung, liver, or kidney disease).
- You are not allergic to local anesthetics (numbing medicines).
- You do not have a history of substance abuse.
- You are not pregnant or breastfeeding, and you have no skin infection at the injection site.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether adding fentanyl or dexmedetomidine to a standard numbing medicine (bupivacaine) provides better pain relief after knee surgery. It may help find the best option for patients undergoing knee procedures like total knee replacement or ACL repair.
This trial tests a combination of two pain-relief methods after total knee replacement: a spinal injection and a nerve block in the thigh. It aims to provide better pain control during and after surgery.
This study compares two different types of nerve blocks to see which provides better pain relief after arthroscopic knee surgery. You will receive one of the blocks after your surgery, and your pain levels will be tracked.
This trial compares two ways to numb the knee area after knee replacement surgery, both using nerve blocks. The goal is to see which approach provides better pain relief and recovery.
This trial tests if adding an extra nerve block behind the knee (IPACK) to the standard block inside the thigh (adductor canal) provides better pain relief after specific knee surgeries. It aims to help patients recover with less opioid use.
This study compares two extra medicines added to the standard numbing medication used for a nerve block during inguinal hernia repair. The goal is to see which medicine provides better pain relief after surgery, while you are under spinal anesthesia (numbness from the waist down).
Hear when a new Postoperative Analgesia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.