Testing a new mRNA therapy for Wilson disease
Part of Brain & nervous system, Digestive system, Genetic & congenital, Hormones & metabolism clinical trials.
This trial tests an experimental mRNA treatment (DSL101) for adults with Wilson disease. It's for people whose condition is stable on current therapy and who have certain genetic markers. The goal is to see if the new treatment can help the body process copper better and reduce the need for standard medicines.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18 or older
- Diagnosed with Wilson disease with two specific gene changes (ATP7B)
- On stable standard treatment (like D-penicillamine or zinc) for at least 6 months
- Willing to follow a low-copper diet throughout the study
- No history of liver transplant or severe liver disease
- No serious depression, suicidal thoughts, or major psychiatric issues in the past 6 months
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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