Clin2
NCT06520059Possibly a fitNot yet recruiting

Knee injections with platelet-rich plasma for severe arthritis

Knee Osteoarthritis

Part of Bones, joints & muscles clinical trials.

This study tests whether two types of platelet-rich plasma (a treatment made from your own blood) can help relieve severe knee osteoarthritis pain when injected into the bone and joint. It may offer a non-surgical option for people whose knee pain limits walking.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
50 people
Ages
45 years and older
Study type
Interventional

Who can take part

  • You have knee osteoarthritis in one or both knees, and an X-ray shows it's severe (grade III or IV).
  • You've had knee symptoms (like pain or stiffness) for more than 3 months.
  • You can walk, but your knee hurts when you do.
  • You have NOT had knee surgery before.
  • You have NOT had knee injections in the last 6 months.
  • You don't have blood platelet disorders, autoimmune diseases, or have not taken certain anti-inflammatory pain meds recently.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05378815Recruiting
Platelet injections for knee arthritis pain

This study tests whether platelet-rich plasma (a treatment made from your own blood) can reduce symptoms of knee osteoarthritis. It focuses on people with specific types of knee pain and X-ray findings, and compares against rules around current pain medicines and injections.

Créteil, Val-De-Marne
NCT06483269Recruiting
Platelet-rich plasma injection for knee arthritis in young athletes

This trial tests using your own platelet-rich plasma (PRP), made from a blood sample, as an injection to treat knee osteoarthritis in active young adults. The goal is to see if it reduces pain and helps you stay active.

Bologna
NCT07784907Recruiting
Platelet-rich plasma and hyaluronic acid for knee arthritis

This trial tests whether a combination of platelet-rich plasma (a concentrate from your own blood) and hyaluronic acid (a joint lubricant) helps reduce pain and improve function in people with knee arthritis. You may be eligible if you have moderate knee pain but your other knee is relatively pain-free.

Chełm, Lublin Voivodeship
NCT07785401Recruiting
Platelet-rich plasma plus hyaluronic acid for knee osteoarthritis

This study tests whether adding platelet-rich plasma (PRP) to hyaluronic acid injections improves knee osteoarthritis pain and function better than hyaluronic acid alone. You may be eligible if you have moderate knee osteoarthritis and no other knee problems.

Warsaw, Masovian Voivodeship
NCT07243392Not yet recruiting
Steroid, dextrose, and platelet-rich plasma injections for knee osteoarthritis

This trial compares three common injection treatments for knee osteoarthritis to see which one works best for pain relief. It tests a steroid, a dextrose solution, and platelet-rich plasma (a treatment made from your own blood).

Lahore, Punjab Province
NCT03491761Recruiting· Phase 2
PRP injection versus hyaluronic acid shots for knee arthritis

This trial tests whether a platelet-rich plasma (PRP) shot works better than a standard hyaluronic acid (“gel”) injection to reduce knee osteoarthritis pain. It may help people with ongoing knee pain choose the treatment that relieves symptoms more effectively.

Skokie, Illinois

Hear when a new Knee Osteoarthritis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.