Resolving early life stress in depression: a psychotherapy study
Part of Brain & nervous system, Mental health clinical trials.
This trial tests if a specific type of psychotherapy can help people with moderate-to-severe depression who experienced stress or adversity in childhood (before age 18). Researchers want to see how the treatment works in the brain and whether it improves depression symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You currently have moderate to severe depression symptoms (as measured by a standard depression scale).
- You experienced some form of stress, difficulty, or adversity before age 18 (such as abuse, neglect, or household challenges).
- You are not currently in regular psychotherapy (you haven't been seeing a therapist consistently in the last 3 months).
- You do not have active suicidal thoughts, plans, or actions that need immediate higher-level care.
- You do not have an active substance use disorder, current mania, or psychosis.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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