Safety study of VVN432 nasal spray
Part of Ear, nose & throat clinical trials.
This trial tests a nasal spray called VVN432 in healthy volunteers and people with chronic sinusitis. It checks if the spray is safe and how the body processes it.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 55 years old.
- For healthy part: you must be in good general health.
- For sinusitis part: you have had sinus symptoms like stuffy nose, mucus, facial pain, or reduced smell for more than 4 weeks.
- Your body mass index (BMI) is between 18.5 and 28.0.
- You are not pregnant, breastfeeding, or planning to become pregnant during the study.
- You have not taken any investigational drug in the last 12 weeks.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new sinus stent that slowly releases medicine to treat chronic sinusitis in both nostrils. The goal is to see if it helps reduce symptoms and inflammation better than usual care.
This study tests a nasal spray made from mastic gum oil, combined with a lower dose of a standard steroid nasal spray, to treat chronic sinusitis (long-lasting inflammation of the sinuses). It may help reduce symptoms with fewer side effects from steroids.
This study is a registry that tracks how well treatments work for people with chronic rhinosinusitis with nasal polyps. By joining, you help doctors learn which therapies lead to better control and possibly remission of symptoms over time.
This study tests a new drug called BBT002 in healthy people and in patients with chronic sinusitis and nasal polyps, with or without asthma. It aims to see if the drug is safe and effective for reducing symptoms.
This trial tests an injection called LP-003 for people with nasal polyps and chronic sinusitis. It aims to reduce symptoms like nasal congestion and improve quality of life. You may qualify if you have tried other treatments and still have symptoms.
This study tests a new medicine called CM326 for people with chronic sinusitis and nasal polyps (growths in the nose). It may help if you still have symptoms despite using steroid sprays or if you cannot take steroids.
Hear when a new Chronic Rhinosinusitis (CRS) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.